Honglin Jin

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Mechanistic insights into LDL nanoparticle-mediated siRNA delivery.

Honglin Jin, Jonathan F Lovell, +7 authors Gang Zheng
Bioconjugate chemistry
2012

Although small interfering RNA (siRNA) can silence the expression of disease-related genes, delivery of these highly charged molecules is challenging. Delivery approaches for siRNAs are actively… (More)

Scavenger Receptor B1 is a Potential Biomarker of Human Nasopharyngeal Carcinoma and Its Growth is Inhibited by HDL-mimetic Nanoparticles

Ying Zheng, Yanyan Liu, +7 authors Zhihong Zhang
Theranostics
2013

Nasopharyngeal carcinoma (NPC) is a very regional malignant head and neck cancer that has attracted widespread attention for its unique etiology, epidemiology and therapeutic options. To achieve high… (More)

Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy.

Yuan Qian, Honglin Jin, +5 authors Zhihong Zhang
Biomaterials
2016

The design of peptide-based subunit vaccine formulations for the direct delivery of tumor antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs) is challenging.… (More)

An (125)I-labeled octavalent peptide fluorescent nanoprobe for tumor-homing imaging in vivo.

Haiming Luo, Jiyun Shi, +4 authors Zhihong Zhang
Biomaterials
2012

Targeting radiopeptides are promising agents for radio-theranostics. However, in vivo evaluation of their targeting specificity is often obscured by their short biologic half-lives and low binding… (More)

The soy-derived peptide Vglycin inhibits the growth of colon cancer cells in vitro and in vivo.

Chang E Gao, Rui Sun, +7 authors Jue-ping Feng
Experimental biology and medicine
2017

Vglycin, a novel natural polypeptide isolated from pea seeds, possesses antidiabetic properties. Our previous studies have shown that Vglycin can induce the differentiation of human colon… (More)

Influence of designer self-assembling nanofiber scaffolds containing anti-cancer peptide motif on hepatoma carcinoma cells.

Ting Liu, Pindong Li, Honglin Jin, Qian Ding, Zhenwei Zou, Gang Peng
Journal of biomedical materials research. Part A
2017

Nanotechnology provides a novel scope for cancer therapeutics. Nanoscale platforms could influence the survival, adhesion, and migration of cancer cells through altering the tumor microenvironments.… (More)

Magnetic Enrichment of Dendritic Cell Vaccine in Lymph Node with Fluorescent-Magnetic Nanoparticles Enhanced Cancer Immunotherapy

Honglin Jin, Yuan Qian, +6 authors Zhihong Zhang
Theranostics
2016

Dendritic cell (DC) migration to the lymph node is a key component of DC-based immunotherapy. However, the DC homing rate to the lymphoid tissues is poor, thus hindering the DC-mediated activation of… (More)

Comparison of caspase-3 activation in tumor cells upon treatment of chemotherapeutic drugs using capillary electrophoresis

Shuang Sha, Honglin Jin, Xiao Li, Jie Yang, Ruiting Ai, Jinling Lu
Protein & Cell
2012

Caspases play important roles in cell apoptosis. Measurement of the dynamics of caspase activation in tumor cells not only facilitates understanding of the molecular mechanisms of apoptosis but also… (More)

Melittin-Containing Hybrid Peptide Hydrogels for Enhanced Photothermal Therapy of Glioblastoma.

Honglin Jin, Guifang Zhao, +8 authors Zhenwei Zou
ACS applied materials & interfaces
2017

The design of biocompatible and efficacious anticancer biomaterials to achieve relatively low tumor recurrence rates is the main pursuit of cancer photothermal therapy (PTT). RADA16-I is a synthetic… (More)

Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel.

Honglin Jin, C. L. Johnny Wan, +11 authors Kunyu Yang
ACS nano
2018

Immunosuppressive tumor microenvironments (TMEs) create tremendous obstacles for an effective cancer therapy. Herein, we developed a melittin-RADA32 hybrid peptide hydrogel loaded with doxorubicin… (More)

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