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BACKGROUND Upregulation of microRNA-221 (miR-221) has been reported to induce the malignant phenotype of human osteosarcoma, suggesting its potential as a therapeutic target for this malignancy. However, the role of miR-221 in diagnosis and prognosis of osteosarcoma has been well less elaborated. Our aim was to investigate the clinicopathological,(More)
Lead, as one of the most hazardous heavy metals to the environment interferes with lignocellulosic biomass bioconversion and carbon cycles in nature. The degradation of lead-polluted lignocellulosic waste and the restrain of lead hazards by solid-state fermentation with Phanerochaete chrysosporium were studied. Phanerochaete chrysosporium effectively(More)
A novel bacterium designated strain B-16 was isolated from the compost leachate of the municipal solid waste (MSW) in a laboratory reactor. This strain was identified as a gram-negative bacterium, Achromobacter xylosoxidans that could grow on bisphenol A (BPA, a representative endocrine disruptor) as a sole carbon source under aerobic condition.(More)
The bark of Magnolia officinalis is a well-known Traditional Chinese Medicine. In the present study, two new alkaloids, named (S)-4-keto-magnoflorine (6) and (R)-3,4-dehydromagnocurarine (11), together with seven known alkaloids: (S)-magnoflorine (5), trans/cis N-feruloylputrescine (7/8), (R)-magnocurarine (10), (S)-tembetarine (12), (R)-oblongine (14), and(More)
Tetrabromobisphenol A (TBBPA) is the most widely used brominated flame retardants (BFRs). It has been detected in various environment media and has been approved to be high toxic to aquatic organisms. However, the exposure levels of TBBPA in the main watersheds in China have not been investigated sufficiently. In this study TBBPA concentrations in water,(More)
The treatment of the simulated lead-contaminated solid waste by composting with white-rot fungus was studied at laboratory scale. The composting system without the inocula of white-rot fungus was prepared as control, and the composting of the uncontaminated solid waste with the inocula of white-rot fungus was carried out as the other control. The results(More)
A Gram-stain-positive, aerobic, motile, rod-shaped bacterium, designated strain Mn1-7(T), was isolated from manganese mining soil in Tianjin, China. The closest phylogenetic relatives were Lysinibacillus massiliensis CCUG 49529(T) (97.2 % 16S rRNA gene sequence similarity), L. xylanilyticus XDB9(T) (96.7 %), L. sinduriensis JCM 15800(T) (96.2 %), L.(More)
Caspases are important regulators and executioners in the apoptosis pathways and play crucial roles in carcinogenesis. We tested the hypothesis that functional variants of CASP genes are associated with risk of squamous cell carcinoma of the head and neck (SCCHN) and second primary malignancy (SPM). We genotyped 7 selected, potentially functional single(More)
Recent studies showed that nonhuman primate TRIM5alpha can efficiently block HIV-1 infection in human cell lines. It can also restrict other retroviruses, therefore, suggested as a general defender against retrovirus infection. Here, we present an evolutionary analysis of TRIM5alpha in primates. Our results demonstrated that TRIM5alpha has been evolving(More)
A gram-negative, aerobic, copper-resistant bacterium, designated strain CU4(T), was isolated from copper mine soil in Daye, China. Phylogenetic analysis based on 16S rRNA gene sequences showed highest similarity to Sphingobium rhizovicinum CC-FH12-1(T) (98.4 %), followed by Sphingobium francense Sp+(T) (97.2 %), Sphingobium japonicum UT26(T) (97.1 %),(More)