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The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
A cancer-promoting histone protein Mutations in the chromatin protein histone H3 are found in a number of pediatric cancers. The lysine-36–to–methionine (K36M) “oncohistone” mutation is seen in… Expand
USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.
Dynamic regulation of RNF168-mediated ubiquitylation of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome… Expand
Genetic effects of XRCC4 and ligase IV genes on human glioma
Ligase IV and XRCC4 genes, important molecules in the nonhomologous end-joining pathway for repairing DNA double-strand breaks, may play crucial roles in carcinogenesis. To detect their effects on… Expand
This information is current as H Physiological Inhibitor of Human Granzyme Identification of SERPINB 1 As a and
Ubc 13-Mediated NF-ERAdP Initiates NK Cell Activation via the The Endoplasmic Reticulum Adaptor Protein
tion of tryptophan metabolism for colorectal cancer therapy : a systematic review
Colorectal cancer (CRC) is one of the most malignant cancers resulting from abnormal metabolism alterations. As one of the essential amino acids, tryptophan has a variety of physiological functions,… Expand