Honglei Chen

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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease…

Stephen S. Lim, Theo Vos, +206 authors Ziad Ahmed Memish
The Lancet
2012

BACKGROUND Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No… (More)

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, Mohsen Naghavi, +188 authors Ziad Ahmed Memish
The Lancet
2012

BACKGROUND Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates. In the Global Burden of Diseases,… (More)

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

C. J. Murray, Theo Vos, +358 authors Ziad Ahmed Memish
The Lancet
2012

BACKGROUND Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of ill-health. The 1990 Global Burden… (More)

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

Mike A. Nalls, Nathan Pankratz, +44 authors Andrew Singleton
Nature Genetics
2014

We conducted a meta-analysis of Parkinson's disease genome-wide association studies using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six loci were identified… (More)

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological…

C. J. Murray, Ryan M Barber, +497 authors Mark G Shrime
The Lancet
2015

BACKGROUND The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and… (More)

Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease

Javier Simón-Sánchez, Claudia Schulte, +43 authors Thomas Gasser
Nature Genetics
2009

We performed a genome-wide association study (GWAS) in 1,713 individuals of European ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases and 4,573 controls, we… (More)

Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women.

Katherine L Tucker, Marian Hannan, Honglei Chen, L. Adrienne Cupples, Peter W. F. Wilson, Douglas P Kiel
The American journal of clinical nutrition
1999

BACKGROUND Osteoporosis and related fractures will be growing public health problems as the population ages. It is therefore of great importance to identify modifiable risk factors. OBJECTIVE We… (More)

Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women.

Sarah L. Booth, Katherine L Tucker, +8 authors Douglas P Kiel
The American journal of clinical nutrition
2000

BACKGROUND Vitamin K has been associated with bone mineral density (BMD) and risk of hip fracture. The apolipoprotein (apo) E4 allele (APOE*E4) has been associated with bone fracture through a… (More)

Hypertension, hypercholesterolemia, diabetes, and risk of Parkinson disease.

Kelly Claire Simon, Honglei Chen, Michael A. Schwarzschild, Alberto A Ascherio
Neurology
2007

OBJECTIVE To determine whether history of hypertension, hypercholesterolemia, or diabetes is associated with risk of Parkinson disease (PD). METHODS Prospective study among participants in two… (More)

Dietary iron intake and risk of Parkinson's disease.

Giancarlo Logroscino, Xiang Gao, Honglei Chen, Al Wing, Alberto A Ascherio
American journal of epidemiology
2008

Dietary iron is the most important source of iron stores. Several case-control studies have described the association of high dietary iron and Parkinson's disease, but prospective data are lacking.… (More)

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