Hongjun He

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The genetic mechanisms mediating the adaptation of Mycobacterium tuberculosis within the host are poorly understood. The best-characterized regulatory systems in this organism include sigma factors and two-component signal transduction systems. mprAB is a two-component system required by M. tuberculosis for growth in vivo during the persistent stage of(More)
Establishment and maintenance of persistent, latent infection by Mycobacterium tuberculosis are dependent on expression of the mprA-mprB regulatory system. Previously, MprA and MprB were shown to participate in phosphotransfer reactions characteristic of two-component signaling systems. To begin identifying downstream effector genes regulated by mprA-mprB(More)
Mycobacterium tuberculosis remains a significant global health concern largely due to its ability to persist for extended periods within the granuloma of the host. While residing within the granuloma, the tubercle bacilli are likely to be exposed to stress that can result in formation of aberrant proteins with altered structures. Bacteria encode stress(More)
To protect hard disk data confidentiality and integrity, AEIVV associates one unique IV with each disk sector; then, it applies authenticated encryption of AES-CCM to the protected sector and constructs hash tree upon IV storage. Through assuring IV to be trusted or un-tampered, data can be protected firmly. To make it an available way for disk protection,(More)
Data encryption is the most important way to provide security in hostile environment. Nearly all of the existing data encryption techniques require a lot of arithmetic and logical computations, which makes their deployment in embedded devices very difficult. To realize firm data encryption without much computation, a novel scheme of physically-embedded data(More)
Hardware/software partitioning is a crucial problem in hardware/software co-design. In this paper, we deeply investigate genetic algorithm (GA) for hardware/software partitioning, our co-design targets a heterogeneous multicore system on chip (SoC) which consists of several different types of processing engines(PE), Communicating structure adopts NOC, We(More)
Clock domain crossing (CDC) is an important issue in integrated circuit (IC) design and verification. In this paper, We present the design of 5 types of CDC schemes in our developed SOC chip with multi working mode and ten clock domain, deeply describe an approach using assertion-based verification (ABV) to verify proper functionality for CDC signals. Taped(More)
To build secure SMP system with resistance against physical attacks, the essential requirements is to make data encryption and data authentication for both the shared bus and the shared memory. Analysis of such problem educes that it must combine the counter mode encryption with the hash tree based authentication, and such combination must inosculate with(More)