Hongchuan Guo

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OBJECTIVE The complete resection of anterior cranial base meningiomas with intra- and extracranial involvement is always challenging. We describe our experience of treating such meningiomas via a purely endoscopic endonasal approach (EEA). METHODS Eight patients with intra- and extradural meningiomas were operated via EEA. In this study, we describe the(More)
Bisphenol A (BPA) is a monomer used in manufacturing a wide range of chemical products, including epoxy resins and polycarbonate. BPA, an important endocrine disrupting chemical that exerts estrogen-like activities, is detectable at nanomolar levels in human serum worldwide. The pregnancy associated doses of 17beta-estradiol (E2) plus tumor-necrosis(More)
Dumbbell-shaped hypoglossal schwannomas with intradural and extradural extension are extremely rare, and complete removal of these tumors is very difficult. This report describes such lesions in three patients that were completely removed via a purely endoscopic transoral approach. Three patients with intradural and extradural growth hypoglossal schwannomas(More)
OBJECTIVE To retrospectively evaluate the effectiveness of the endoscopic endonasal removal of pituitary adenomas (PAs) with paraclival internal carotid artery (ICA) invasion. METHODS Between February 2002 and August 2009, 14 consecutive patients underwent 'pure' extended endonasal transsphenoidal endoscopic surgery for PAs with paraclival ICA invasion.(More)
Skull base chordomas are invasive tumors, with high rate of local recurrence even when totally extracted. The aggressive biological behavior in chordoma remains unclear. The purpose of this study was to investigate the relationship between fascin expression and tumor biological behavior in skull base chordoma. Using immunohistochemical techniques, we(More)
OBJECTIVE To evaluate the efficiency of the descending hypoglossal branch-facial nerve anastomosis for the severe facial palsy after acoustic neuroma resection. METHODS The clinical data of 14 patients (6 males, 8 females, average age 45. 6 years old) underwent descending hypoglossal branch-facial nerve anastomosis for treatment of unilateral facial palsy(More)
OBJECTIVE Hypoglossal nerve schwannoma, especially when inside the extracranial region, is extremely rare. This report describes a new endoscopic transoral approach for the removal of extracranial hypoglossal schwannoma. PATIENTS AND METHODS Three patients (1 male and 2 females, aged 58-63 years) with extracranial hypoglossal schwannoma in the(More)
Glioblastoma multiforme (GBM) is among the most lethal of all human tumors. It is the most frequently occurring malignant primary brain tumor in adults. The current standard of care (SOC) for GBM is initial surgical resection followed by treatment with a combination of temozolomide (TMZ) and ionizing radiation (IR). However, GBM has a dismal prognosis, and(More)
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