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YAP and ERK mediated mechanical strain‐induced cell cycle progression through RhoA and cytoskeletal dynamics in rat growth plate chondrocytes
Yes‐associated protein (YAP) and extracellular signal‐regulated kinase (ERK) have been considered as key regulators in tissue homeostasis, organ development, and tumor formation. However, the rolesExpand
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Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis
Osteoarthritis (OA) is a highly prevalent joint disorder blamed for pain and disability in older individuals. It’s commonly accepted that inflammation, apoptosis, autophagy and cellular senescenceExpand
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p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes
Osteoarthritis (OA) is a common chronic inflammatory joint disease characterized by cartilage degradation. p-Coumaric acid (PCA), a dietary phenolic compound, has exerted anti-inflammatory andExpand
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Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis.
Osteoarthritis (OA), a degenerative arthropathy, is featured with progressive degradation of cartilage and a chondrocyte inflammatory response. Erdosteine (ER) showed the anti-oxidant properties andExpand
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Directional Differentiation of Bone Marrow Mesenchymal Stem Cells into Oligodendrocytes Induced by the Combination of Various Neurotrophic Factors
BACKGROUND: Myelination following axonal regeneration is a key factor affecting the recovery of spinal cord injury. Oligodendrocyte survival directly affects the myelination following axonalExpand
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Tomatidine suppresses inflammation in primary articular chondrocytes and attenuates cartilage degradation in osteoarthritic rats
In this study, we investigated whether the anti-inflammatory effects of tomatidine alleviate osteoarthritis (OA)-related pathology in primary articular chondrocytes and a rat OA model. STITCHExpand
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Comparison of different anesthesia techniques on early prognosis in patients undergoing hip joint replacement
Objective To compare the effects of different anesthesia techniques on early prognosis in patients undergoing hip joint replacement. Methods The demographic, preoperative and postoperativeExpand
Ectopic chondrogenesis of composite of enhanced green fluorescent protein gene-modified precartilaginous stem cells and bone matrix gelatin
Objective To evaluate the chondrogenesis potential of composite of enhanced green fluorescent protein (EGFP) gene-modified precartilaginous stem cells (PSCs) and bone matrix gelatin (BMG)Expand
Effect of cefazolin loaded bone matrix gelatin on repairing large segmental bone defects and preventing infection.
  • Hongbo You, A. Chen
  • Chemistry, Medicine
  • Chinese journal of traumatology = Zhonghua chuang…
  • 1 August 2004
OBJECTIVE To explore the possibility of repairing long segmental bone defects and preventing infection with cefazolin loaded bone matrix gelatin (C-BMG). METHODS C-BMG was made from puttingExpand
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Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways
Osteoarthritis (OA), in which inflammation plays a crucial role, is the most common joint disease characterized by cartilage degradation. Neferine (Nef), a dibenzyl isoquinoline alkaloid, has shownExpand