Share This Author
Segmentation of M-FISH Images for improved classification of chromosomes with an adaptive fuzzy c-means clustering algorithm
An adaptive fuzzy c-means (AFCM) clustering based algorithm was developed and applied to the segmentation and classification of multi-color fluorescence in situ hybridization (M-FISH) images, which…
Integrating fMRI and SNP data for biomarker identification for schizophrenia with a sparse representation based variable selection method
- Hongbao Cao, Junbo Duan, D. Lin, V. Calhoun, Yu-ping Wang
- Medicine, PsychologyBMC Medical Genomics
- 11 November 2013
The proposed SRVS algorithm is effective in identifying significant biomarkers for complicated disease as SCZ and suggests the advantage of integrative analysis of different types of data.
Multi-trait analysis for genome-wide association study of five psychiatric disorders
A cross-trait meta-analysis of genome-wide association study on schizophrenia, bipolar disorder, autism spectrum disorder, attention deficit hyperactivity disorder, and depression revealed the existence of two clusters of related psychiatric conditions that were separate from the other three traits and formed another group.
Association of telomere length and mitochondrial DNA copy number with risperidone treatment response in first-episode antipsychotic-naïve schizophrenia
Accumulating evidence indicates a putative association of telomere length and mitochondrial function with antipsychotics response in schizophrenia (SCZ). However, pharmacological findings were…
Sparse representation based biomarker selection for schizophrenia with integrated analysis of fMRI and SNPs
Causal influences of neuroticism on mental health and cardiovascular disease.
It is indicated that genetic variation mediates the causal influences of neuroticism on mental health and cardiovascular diseases.
Identifying common genome-wide risk genes for major psychiatric traits
Income is provided into the shared genetic liability among major psychiatric traits and the long non-coding gene LINC00461 showed the highest pleiotropic effects on five psychiatric traits.
Sparse models for correlative and integrative analysis of imaging and genetic data
Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement
It is suggested that TD may be associated with the alterations in GMV that are different from that of schizophrenics without TD, and further studies are needed to confirm and to examine the functional significance of these structural findings.
Efficient test for nonlinear dependence of two continuous variables
This work proposed a new way of testing nonlinear dependence between two continuous variables (X and Y) by using CANOVA (continuous analysis of variance, software available at https://sourceforge.net/projects/canova/).