Hong-lin Song

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In the present study we describe the complete cytochrome P450 complement, the "CYPome," of Streptomyces coelicolor A3(2). Eighteen cytochromes P450 (CYP) are described, in contrast to the absence of CYPs in Escherichia coli, and the twenty observed in Mycobacterium tuberculosis. Here we confirm protein identity as cytochromes P450 by heterologous expression(More)
OBJECTIVE To observe the effects of WWOX on cell attachment in ovarian cancer, and to explore its mechanisms of action. METHODS Attachment assay was used to assess the adhesion of wwox-transfected PEO1 cells and vector-transfected PEO1 cells that were constructed, as well as PEO1 parent cells. Alpha/beta integrin-mediated cell adhesion assays were(More)
OBJECTIVE To explore the relationship between WWOX gene and attachment and adhesion of ovarian cancer. METHODS The expression of WWOX mRNA was detected by RT-PCR, the expression of the WWOX protein was evaluated by western blot in WWOX-transfected PEO1 cells (H6, H7, H8 cell) and vector-transfected control cells (vec-1, vec-2 cell). Attachment assay was(More)
BACKGROUND To evaluate HPV testing by Hybrid Capture II (HCII) in conjunction with cytology in detecting the residual/recurrence disease after treatment of high-grade cervical intraepithelial neoplasia (CIN II-III) with loop electrosurgical excision procedure (LEEP). MATERIALS AND METHODS A retrospective review of 158 patients with histologically(More)
OBJECTIVE To explore the diagnostic value of serum vascular endothelial growth factor (VEGF) level in patients with ovarian carcinomas, and to evaluate the correlation between serum VEGF level and prognosis of ovarian cancer. METHOD Serum VEGF level in patients with ovarian neoplasms (120 cases of ovarian carcinomas, 25 cases of benign tumors) and 90(More)
OBJECTIVE To evaluate the relationship between bcl-2 gene and endometrial carcinoma. METHODS Immunohistochemical staining was performed on formalin-fixed paraffin-embedded tissue sections. A monoclonal antibody to the bcl-2 gene product was used, the signal was detected using a streptavidin-biotin complex with aminoethylcarbazole. There were 15 cases of(More)
BACKGROUND Whether concurrent chemotherapy treatment is superior to radiotherapy alone as an adjuvant regimen for postoperative cervical carcinoma with risk factors remains controversial. MATERIALS AND METHODS A literature search strategy was used to examine Pubmed, Embase, the Cochrane Library, the China National Knowledge Internet Web, the Chinese(More)
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