Hong-jun Zhu

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Phthalic acid diamides have received considerable interest in agricultural chemistry due to a novel action mode, extremely high activity against a broad spectrum of lepidopterous insects, low acute toxicity to mammals, and environmentally benign characteristics. A series of phthalic acid diamides (4I-4IV) with the CF3 group at meta position on the aniline(More)
AIM To investigate the protective effect of triptolide (TRI) on ischemia/reperfusion-induced injury of transplanted rabbit lungs and to investigate the mechanisms underlying the actions of TRI. METHODS We established the rabbit lung transplantation model and studied lung injury induced by ischemia/reperfusion and the inhibitory effect of TRI on NF-kappaB.(More)
  • Hong-Jun Zhu, De-Guo Wang, Ji Yan, Jian Xu
  • American journal of translational research
  • 2015
BACKGROUND AND AIMS The heart in diabetic state is sensitive to myocardial ischemia reperfusion (mI/R) injury. In the present study, we investigated the potential mechanisms of modulating mI/R injury in diabetic state. METHODS Diabetic db/db mice and control non-diabetic mice were administrated with mI/R injury or sham operation. Mouse atrial-derived(More)
Mesenchymal stem cells (MSCs) with elevated levels of connexin 43 (Cx43) have been shown to exhibit improved protection for ischemic hearts. However, it remains unclear whether Cx43 is involved in the paracrine actions of angiogenesis, the major mechanism of cell therapy. In the present study, an in vitro model with deprivation of oxygen and a murine(More)
A series of 4,8-substituted 1,5-naphthyridines (1a-1h) have been successfully synthesised by a Suzuki cross-coupling between 4,8-dibromo-1,5-naphthyridine (4) and the corresponding boronic acids (2a-2h) in the presence of catalytic palladium acetate in yields of 41.4-75.8% and have ben well characterized. They are thermally robust with high phase transition(More)
BACKGROUND Phthalic acid diamide derivatives are among the most important classes of synthetic insecticides. In this study, a 3,3-dichloro-2-propenyloxy group, the essential active group of pyridalyl derivatives, was incorporated into phthalic acid diamide derivatives with the aim of combining the active groups to generate more potent insecticides. (More)
OBJECTIVE To observe the intervention effects of Liandou Qingmai Recipe (LQR) on atherogenic indices of plasma (AIP) and high-sensitivity c-reactive protein (hs-CRP) level in patients with coronary heart disease (CHD). METHODS Sixty-eight CHD patients were randomly assigned to two groups, 35 patients in the treatment group and 33 in the control group, all(More)
BACKGROUND Anthranilic diamide insecticides containing pyridylpyrazole-5-carboxamide are extremely important in modern agriculture. New structurally modified compounds with high insecticidal activity were discovered by designing a series of novel pyridylpyrazole-4-carboxamides (9I to 9IV) and pyridylpyrazole-4-carboxamides (10I to 10IV), the latter designed(More)
The title mol-ecule, C(16)H(16)Br(2)O(8), lies on a crystallographic twofold axis. Weak intra-molecular C-H⋯O hydrogen bonds may, in part, control the conformation of the mol-ecule. In the crystal structure, mol-ecules are connected into a two-dimensional network via weak inter-molecular C-H⋯O hydrogen bonds.