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- Claire J Whitehouse, Richard M. Taylor, +5 authors Keith W. Caldecott
- Cell
- 2001
XRCC1 protein is required for DNA single-strand break repair and genetic stability but its biochemical role is unknown. Here, we report that XRCC1 interacts with human polynucleotide kinase in… (More)
- Ye Tian, Zhipeng Li, +11 authors Hong Zhang
- Cell
- 2010
The molecular understanding of autophagy has originated almost exclusively from yeast genetic studies. Little is known about essential autophagy components specific to higher eukaryotes. Here we… (More)
- Ian S Roberts, H. Terence Cook, +41 authors Hong Zhang
- Kidney international
- 2009
Pathological classifications in current use for the assessment of glomerular disease have been typically opinion-based and built on the expert assumptions of renal pathologists about lesions… (More)
- Hang Cui, Yahui Kong, Hong Zhang
- Journal of signal transduction
- 2012
Aging is an intricate phenomenon characterized by progressive decline in physiological functions and increase in mortality that is often accompanied by many pathological diseases. Although aging is… (More)
- Yuxia Zhang, Libo Yan, +9 authors Hong Zhang
- Cell
- 2009
How autophagy, an evolutionarily conserved intracellular catabolic system for bulk degradation, selectively degrades protein aggregates is poorly understood. Here, we show that several maternally… (More)
- Katharine O. Hartley, David Gell, +7 authors Stephen P. Jackson
- Cell
- 1995
DNA-dependent protein kinase (DNA-PK), which is involved in DNA double-stranded break repair and V(D)J recombination, comprises a DNA-targeting component called Ku and an approximately 460 kDa… (More)
- Yusuke Kato, Tomoyasu Aizawa, Hirokazu Hoshino, Keiichi Kawano, Katsutoshi Nitta, Hong Zhang
- The Biochemical journal
- 2002
Two genes encoding the ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptide, abf-1 and abf-2, were identified in Caenorhabditis elegans. Recombinant ABF-2 exhibited potent… (More)
The transforming growth factor-beta (TGF-beta) family of cytokines regulates vascular development and inflammatory responses. We have recently shown that exposure of human umbilical vein endothelial… (More)
- Rosanna Coppo, Stéphan Troyanov, +41 authors Hong Zhang
- Kidney international
- 2010
To study the predictive value of biopsy lesions in IgA nephropathy in a range of patient ages we retrospectively analyzed the cohort that was used to derive a new classification system for IgA… (More)
- S. Y. Xiao, Hong Zhang, Hilda Guzmán, Robert B. Tesh
- The Journal of infectious diseases
- 2001
Subadult and adult hamsters were inoculated intraperitoneally with 10(6) TCID(50) of yellow fever (YF) virus (Jimenez strain). Four animals from each group were subjected daily to histologic… (More)