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Cancer stem cells (CSCs), or tumor-initiating cells, are involved in tumor progression and metastasis. MicroRNAs (miRNAs) regulate both normal stem cells and CSCs, and dysregulation of miRNAs has been implicated in tumorigenesis. CSCs in many tumors--including cancers of the breast, pancreas, head and neck, colon, small intestine, liver, stomach, bladder(More)
Auditory brainstem response (ABR) techniques, an electrophysiological far-field recording method widely used in clinical evaluation of human hearing, were adapted for fishes to overcome the major limitations of traditional behavioral and electrophysiological methods (e.g., invasive surgery, lengthy training of fishes, etc.) used for fish hearing research.(More)
Today's data networks are surprisingly fragile and difficult to manage. We argue that the root of these problems lies in the complexity of the control and management planes--the software and protocols coordinating network elements--and particularly the way the decision logic and the distributed-systems issues are inexorably intertwined. We advocate a(More)
We present Tesseract, an experimental system that enables the direct control of a computer network that is under a single administrative domain. Tesseract’s design is based on the 4D architecture, which advocates the decomposition of the network control plane into decision, dissemination, discovery, and data planes. Tesseract provides two primary abstract(More)
It is well known that at low-bit-rate block discrete cosine transform compressed image exhibits visually annoying blocking and ringing artifacts. In this paper, we propose a noniterative, wavelet-based deblocking algorithm to reduce both types of artifacts. The algorithm exploits the fact that block discontinuities are constrained by the dc quantization(More)
In this paper, we propose an analytic-to-holistic approach which can identify faces at different perspective variations. The database for the test consists of 40 frontal-view faces. The first step is to locate 15 feature points on a face. A head model is proposed, and the rotation of the face can be estimated using geometrical measurements. The positions of(More)
This paper describes a modi"ed logical thresholding method for binarization of seriously degraded and very poor quality gray-scale document images. This method can deal with complex signal-dependent noise, variable background intensity caused by nonuniform illumination, shadow, smear or smudge and very low contrast. The output image has no obvious loss of(More)