Hong-Yan Zheng

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The breast cancer stem cells (BCSC) play important roles in breast cancer occurrence, recurrence and metastasis. However, the role of estrogen signaling, a signaling pathway important in development and progression of breast cancer, in regulation of BCSC has not been well established. Previously, we identified and cloned a variant of estrogen receptor α,(More)
Partially observable Markov decision process (POMDP) is an ideal framework for sequential decision-making under uncertainty in stochastic domains. However, it is notoriously computationally intractable to solving POMDP in real-time system. In order to address this problem, this paper proposes a point-based online value iteration (PBOVI) algorithm which(More)
—Learning the enormous number of parameters is a challenging problem in model-based Bayesian reinforcement learning. In order to solve the problem, we propose a model-based factored Bayesian reinforcement learning (F-BRL) approach. F-BRL exploits a factored representation to describe states to reduce the number of parameters. Representing the conditional(More)
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