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- Lan-Juan Zhao, Hui Jiang, +4 authors Hong-Wen Deng
- Journal of bone and mineral research : the…
- 2008
It was previously believed that obesity and osteoporosis were two unrelated diseases, but recent studies have shown that both diseases share several common genetic and environmental factors. Body fat… (More)
- Yong-Jun Liu, Xiao-gang Liu, +14 authors Hong-Wen Deng
- Human molecular genetics
- 2008
Obesity is a major public health problem with strong genetic determination; however, the genetic factors underlying obesity are largely unknown. In this study, we performed a genome-wide association… (More)
- Lan-Juan Zhao, Yong-Jun Liu, Peng-Yuan Liu, James Hamilton, Robert Roy Recker, Hong-Wen Deng
- The Journal of clinical endocrinology and…
- 2007
CONTEXT
The relationship between obesity and osteoporosis has been widely studied, and epidemiological evidence shows that obesity is correlated with increased bone mass. Previous analyses, however,… (More)
- Qing-yang Huang, Fu-Hua Xu, +6 authors Hong-Wen Deng
- American journal of human genetics
- 2002
Microsatellites are a major type of molecular markers in genetics studies. Their mutational dynamics are not clear. We investigated the patterns and characteristics of 97 mutation events… (More)
- Hong-Wen Deng, W. M. Chen, +5 authors R. R. Recker
- Genetic epidemiology
- 2000
In 40 human pedigrees with 563 subjects, we evaluated the contribution of genetic and life-style factors (exercise, smoking, and alcohol consumption) and the interactions between non-genetic factors… (More)
- Yu-Fang Pei, Jian Li, Lei Zhang, Christopher J. Papasian, Hong-Wen Deng
- PloS one
- 2008
The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to… (More)
- Jian-feng Liu, Yongjun Liu, Xiaogang Liu, Hong-Wen Deng
- American journal of human genetics
- 2007
Complex traits important for humans are often correlated phenotypically and genetically. Joint mapping of quantitative-trait loci (QTLs) for multiple correlated traits plays an important role in… (More)
- Dong-hai Xiong, Hui Shen, +8 authors Hong-Wen Deng
- Journal of bone and mineral research : the…
- 2006
UNLABELLED
Many "novel" osteoporosis candidate genes have been proposed in recent years. To advance our knowledge of their roles in osteoporosis, we screened 20 such genes using a set of high-density… (More)
- Dong-hai Xiong, Xiao-gang Liu, +26 authors Hong-Wen Deng
- American journal of human genetics
- 2009
To identify and validate genes associated with bone mineral density (BMD), which is a prominent osteoporosis risk factor, we tested 379,319 SNPs in 1000 unrelated white U.S. subjects for associations… (More)
- Hong-Wen Deng, W. M. Chen, R. R. Recker
- Genetics
- 2001
In association studies searching for genes underlying complex traits, the results are often inconsistent, and population admixture has been recognized qualitatively as one major potential cause.… (More)