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- Lan-Juan Zhao, Hui Jiang, +4 authors Hong-Wen Deng
- Journal of bone and mineral research : the…
- 2008
It was previously believed that obesity and osteoporosis were two unrelated diseases, but recent studies have shown that both diseases share several common genetic and environmental factors. Body fat… (More)
- Lan-Juan Zhao, Yong-Jun Liu, Peng-yuan Liu, J. Paul Hamilton, Robert Roy Recker, Hong-Wen Deng
- The Journal of clinical endocrinology and…
- 2007
CONTEXT
The relationship between obesity and osteoporosis has been widely studied, and epidemiological evidence shows that obesity is correlated with increased bone mass. Previous analyses, however,… (More)
- H Li, Tuomas O Kilpeläinen, +62 authors R. J. F. Loos
- Diabetologia
- 2011
FTO harbours the strongest known obesity-susceptibility locus in Europeans. While there is growing evidence for a role for FTO in obesity risk in Asians, its association with type 2 diabetes,… (More)
- Lingjun Zuo, Joel Gelernter, +11 authors Xingguang Luo
- Neuropsychopharmacology
- 2012
Previous studies using SAGE (the Study of Addiction: Genetics and Environment) and COGA (the Collaborative Study on the Genetics of Alcoholism) genome-wide association study (GWAS) data sets reported… (More)
- Y P Liu, Xiao-gang Liu, +14 authors Hong-Wen Deng
- Human molecular genetics
- 2008
Obesity is a major public health problem with strong genetic determination; however, the genetic factors underlying obesity are largely unknown. In this study, we performed a genome-wide association… (More)
- Q Huang, Fu-Hua Xu, +6 authors Hong-Wen Deng
- American journal of human genetics
- 2002
Microsatellites are a major type of molecular markers in genetics studies. Their mutational dynamics are not clear. We investigated the patterns and characteristics of 97 mutation events… (More)
- Dong-hai Xiong, Xiao-gang Liu, +26 authors Hong-Wen Deng
- American journal of human genetics
- 2009
To identify and validate genes associated with bone mineral density (BMD), which is a prominent osteoporosis risk factor, we tested 379,319 SNPs in 1000 unrelated white U.S. subjects for associations… (More)
- Dong-hai Xiong, Hui Shen, +8 authors Hong-Wen Deng
- Journal of bone and mineral research : the…
- 2006
UNLABELLED
Many "novel" osteoporosis candidate genes have been proposed in recent years. To advance our knowledge of their roles in osteoporosis, we screened 20 such genes using a set of high-density… (More)
- Tielin Yang, Xiang-ding Chen, +23 authors Hong-Wen Deng
- American journal of human genetics
- 2008
Osteoporosis, a highly heritable disease, is characterized mainly by low bone-mineral density (BMD), poor bone geometry, and/or osteoporotic fractures (OF). Copy-number variation (CNV) has been shown… (More)
- Peter M. Visscher, Stuart Macgregor, +11 authors Nicholas G. Martin
- American journal of human genetics
- 2007
Height has been used for more than a century as a model by which to understand quantitative genetic variation in humans. We report that the entire genome appears to contribute to its additive genetic… (More)