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We develop an ELLAM (Eulerian-Lagrangian localized adjoint method) scheme to solve two-dimensional advection-diiusion equations with all combinations of innow and outtow Dirichlet, Neumann, and ux boundary conditions. The ELLAM formalism provides a systematic framework for implementation of general boundary conditions, leading to mass-conservative numerical(More)
The symmetric encryption problem which manifests itself when two parties must securely transmit a message m with a short shared secret key is considered in conjunction with a computationally unbounded adversary. As the adversary is unbounded, any encryption scheme must leak information about m; in particular, the mutual information between m and its(More)
In this study, an experimental rat ligated heart model was used to observe the effect of treatment with carvedilol, metoprolol and metoprolol plus a highly selective alpha(1)-adrenergic blocking agent, bunazosin, after acute myocardial infarction (MI). Compared with an untreated MI group, all drug-treated groups demonstrated attenuation of inflammatory(More)
Metabolism is a very important cellular process and its malfunction contributes to human disease. Therefore, building dynamic models for metabolic networks with experimental data in order to analyze biological process rationally has attracted a lot of attention. Owing to the technical limitations, some unknown parameters contained in models need to be(More)
BACKGROUND Multitrait analysis of quantitative trait loci can capture the maximum information of experiment. The maximum-likelihood approach and the least-square approach have been developed to jointly analyze multiple traits, but it is difficult for them to include multiple QTL simultaneously into one model. RESULTS In this article, we have successfully(More)
PURPOSE Surgeons often can contribute failure of sphincter-preserving procedure to a limitation of pelvis anatomy; however, they cannot determine definitely which anatomic diameter or spatial factor actually affected the success of the procedure. METHODS Colorectal surgeons, radiologists, and research fellows collaborated closely to establish a(More)
The key objective of NMPC is to find the best vector of control functions that minimize or maximize a performance index depending on a given process model (usually a nonlinear differential equation system) as equality constraints, and boundary conditions as inequality constraints on the states and controls. The use of process optimization in the control of(More)