Hong Sun Jang

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BACKGROUND Melanoma of unknown primary (MUP) is a condition of metastatic melanoma without a primary lesion. OBJECTIVE We sought to identify the prognosis of MUP compared with melanoma of known primary (MKP). METHODS We searched for observational studies containing at least 10 patients with MUP from MEDLINE and EMBASE from inception to December 22,(More)
Many reports have described the presence of alopecia areata (AA) associated with other autoimmune diseases, which support the autoimmune nature of AA. Additionally, AA has been reported in association with malignancy as a paraneoplastic symptom. In this report, we describe three patients with diffuse large B-cell lymphoma, alveolar soft part sarcoma, and(More)
BACKGROUND Genetic alterations have been identified in melanomas according to different levels of sun exposure. Whereas the conventional morphology-based classification provides a clue for tumor growth and prognosis, the new classification by genetic alterations offers a basis for targeted therapy. OBJECTIVE The purpose of this study is to demonstrate the(More)
squamous cell carcinoma in situ associated with erythema ab igne. Arch Dermatol 1979; 115: 1226–1228. 9 Jones CS, Tyring SK, Lee PC, et al. Development of neuroendocrine (Merkel cell) carcinoma mixed with squamous cell carcinoma in erythema ab igne. Arch Dermatol 1988; 124: 110–113. 10 Wharton J, Roffwarg D, Miller J, et al. Cutaneous marginal zone lymphoma(More)
BACKGROUND In cases of early stage subungual melanoma (SUM), conservative treatment with non-amputative wide excision of the nail unit and subsequent skin graft is preferred over amputation to preserve the involved digit. OBJECTIVE We report a series of patients with SUM treated with conservative surgery and suggest an effective supplementary treatment(More)
398 Ann Dermatol Received October 17, 2012, Revised November 25, 2012, Accepted for publication November 28, 2012 Corresponding author: Sang Ho Oh, Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, Korea. Tel: 82-2-2228-2080, Fax:(More)
Cutaneous squamous cell carcinomas and keratoacanthomas commonly occur in patients treated with BRAF inhibitors. We investigated the effect of the BRAF inhibitor vemurafenib on normal immortalized human HaCaT keratinocytes to explore the mechanism of hyperproliferative cutaneous neoplasia associated with the use of BRAF inhibitors. Vemurafenib induced an(More)
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