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MiR-27a-3p promotes esophageal cancer cell proliferation via F-box and WD repeat domain-containing 7 (FBXW7) suppression.
- Xue-Zhi Wu, Kui-Peng Wang, Hong-Jie Song, Jian-Hua Xia, Yan Jiang, Yong-lian Wang
- International journal of clinical and…
- 15 September 2015
The findings indicated that miR-27a-3p could be considered as a potential therapeutic strategy for ESCC therapy, and explored mechanisms underlying the promotive role. Expand
Overexpression of CST4 promotes gastric cancer aggressiveness by activating the ELFN2 signaling pathway.
It is shown that cystatin 4 (CST4) is markedly upregulated in gastric cancer cell lines and clinical tissues and it is demonstrated that CST4 enhanced gastric cancers aggressiveness by regulating ELFN2 signaling. Expand
MiR-27 a-3 p promotes esophageal cancer cell proliferation via F-box and WD repeat domain-containing 7 ( FBXW 7 ) suppression
Emerging evidence has suggested that dysregulation of microRNA-27a-3p (miR-27a-3p) may contribute to tumor development and progression in various types of cancers. However, its role in esophageal… Expand
The Relationship between the Expression of p27Kip1, p53 and the Infiltration, Metastasis and Prognosis in Gastric Carcinoma
The expression of p27Kip1 is more useful than that of p53 in the prognosis prediction of gastric carcinoma and was a stronger independent survival predictor than p53 expression. Expand
Overexpression of CST 4 promotes gastric cancer aggressiveness by activating the ELFN 2 signaling pathway
Gastric cancer is one of the most lethal malignancies of gastrointestinal cancer and its prognosis remains dismal because of the paucity of effective therapeutic targets. Here, we show that cystatin… Expand