Hong An Jack Huang

Learn More
The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a marker for Parkinson's disease (Pd) and attention deficit hyperactivity disorder (ADHD). In ADHD, DAT density levels are elevated, while in Pd these levels are depleted. The depletion of DAT levels also corresponds with the loss of dopamine. We now describe the design,(More)
Combination studies of neurokinin 1 (NK1) receptor antagonists and serotonin-selective reuptake inhibitors (SSRIs) have shown promise in preclinical models of depression. Such a combination may offer important advantages over the current standard of care. Herein we describe the discovery and optimization of an indazole-based chemotype to provide a series of(More)
—In this paper, the problem of tracking convoys using Ground Moving Target Indicator (GMTI) radar systems is investigated. Some relevant techniques are reviewed. An approach to exploit group information, road map, and Doppler blindness information in convoy tracking is proposed. Simulated measurement data are used to evaluate the performance against a(More)
  • 1