Hollin M. Buck

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Exposure to acute stress has been shown to increase the expression of pro-inflammatory cytokines in brain, blood and peripheral organs. However, the nature of the inflammatory response evoked by acute stress varies depending on the stressor used and species examined. The goal of the following series of studies was to characterize the consequences of social(More)
BACKGROUND Evidence has emerged demonstrating that ethanol (EtOH) influences cytokine expression within the central nervous system, although most studies have examined long-term exposure. Thus, the cytokine response to an acute EtOH challenge was investigated, in order to characterize profiles of cytokine changes following acute exposure. METHODS Rats(More)
Alcohol withdrawal is associated with reduced activity, increased anxiety, and other signs of distress. The goal of the current studies was to determine whether acute ethanol exposure would alter hypothalamic–pituitary–adrenal (HPA) axis reactivity and cytokine responses to stress challenges imposed during the withdrawal period. Male Sprague–Dawley rats(More)
Exposure to an immunogen results in a constellation of behavioral changes collectively referred to as "sickness behaviors," with alterations in cytokine expression previously shown to contribute to this sickness response. Since behaviors observed during ethanol withdrawal are strikingly similar to sickness behaviors, we hypothesized that behavioral(More)
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