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Repetitive occurrence of partial or total upper airway obstruction characterizes several respiratory dysfunctions such as the obstructive sleep apnea syndrome (OSAS). In OSAS patients, pharyngeal collapses are linked to a decrease in upper airway muscle activity during sleep which causes decreased upper airway wall stiffness. Continuous positive airway(More)
Detecting and differentiating central and obstructive respiratory events is an important aspect of the diagnosis of sleep-related breathing disorders with respect to the choice of an appropriate treatment. The purpose of this study was to evaluate the performance of a new algorithm for automated detection and classification of apneas and hypopneas, compared(More)
Patients with pulmonary disease are often unable to complete forced expiration manœuvres. The aim of the study is to evaluate whether forced vital capacity (FVC), the volume exhaled at the end of completed forced expiration, can be estimated by extrapolating volume-time curves obtained from uncompleted manœuvres. The suitability of mono-, bi-, and(More)
BACKGROUND The forced oscillation technique (FOT) allows analysis of the upper airway impedance and, hence, detection of obstructive sleep apnea. OBJECTIVE To evaluate FOT with respect to sensitivity and to specificity in online detection of sleep-disordered breathing patterns and to compare algorithmic onset detection time with manual onset time markers(More)
Pharyngeal collapse in patients with obstructive sleep apnea syndrome (OSAS) is linked to decreased upper airway muscle activity. We hypothesised that decreased muscle activity causes decreased stiffness of the upper airway wall and assumed that a decrease in wall stiffness would result in a change point (CP) of the morphology of phase angle time series(More)
BACKGROUND Vital capacity is a key parameter in the determination of lung function, usually assessed by means of a forced expiration maneuver. This maneuver can be exhausting, and patients often cannot complete it. OBJECTIVES This study evaluates a method to estimate forced vital capacity (FVC) based on the extrapolation of volume-time curves from forced(More)
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