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It is widely accepted that human immunodeficiency virus (HIV) invades the central nervous system (CNS) shortly after peripheral infection to establish a persistent infection of tissue-resident microglial cells. To what extent this early CNS infection is of pathogenic relevance is a matter of discussion. It is conceivable, however, that infected microglia(More)
Potassium deficiency was induced in rats by feeding a potassium- free synthetic diet containing 5% Resonium A. Feeding this diet for 1 week resulted in a decrease of plasma potassium by about 50% vs. pair fed controls. In hypokalemic rats hepatic fatty-acid synthesis and TG secretion by the liver were significantly reduced. In contrast the removal of an(More)
In bilaterally nephrectomized rats fatty acid synthesis (incorporation of 3H from 3H2O into fatty acids by the liver) and triacylglycerol (TG) secretion by the liver (Triton method) were investigated 24 h after surgery. Starved and fed rats were employed. In uremic rats fatty acid synthesis occurs at a normal rate; prevention of acidosis during uremia by(More)
Katacalcin is a recently discovered peptide, contained within the calcitonin precursor. For the highly sensitive radioimmunological measurement of katacalcin and calcitonin we used extraction on C-18, thereby lowering the detection limits in serum to 0.8 pmol/l (katacalcin) and 0.7 pmol/l (calcitonin), and simultaneously improving the specificities of both(More)
iCT was determined in 74 patients by direct RIA. A highly significant increase (371 pg/ml) compared with normal serum concentration (100 pg/ml) was observed. There was no correlation between iCT concentration and ejaculate parameters. In addition monomeric bioactive CT and from the same RNA derived KT were determined from a seminal plasma pool gathered from(More)