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PURPOSE AND METHODS Optimization of remission-induction and postremission therapy in elderly individuals with acute myeloid leukemia (AML) was the subject of a randomized study in patients older than 60 years. Remission-induction chemotherapy was compared between daunomycin (DNR) 30 mg/m2 on days 1, 2, and 3 versus mitoxantrone (MTZ) 8 mg/m2 on days 1, 2,(More)
Multiple endocrine neoplasia type 2A (MEN2A) is an autosomal dominantly inherited cancer syndrome characterized by medullary carcinoma of the thyroid, phaeochromocytoma and hyperparathyroidism. Almost all gene carriers can be detected by screening tests before the age of 40, but the nature and location of the predisposing gene are unknown. Simpson et al.(More)
Sacral insufficiency fractures (SIF) usually occur in elderly women and are secondary to various conditions, mainly postmenopausal or steroid-induced osteoporosis and radiation therapy. They are often overlooked or confused clinically and radiographically with metastatic disease. We report a case of a 72-year-old woman who presented to our department with(More)
Complications and side effects in any kind of surgery, especially in spine surgery, should be evaluated to prevent those problems in the future. Since retrospective studies are of minor value and randomized controlled studies for complications are impossible to perform because of ethical and legal reasons, so-called "expert opinion" has to take their place(More)
STUDY DESIGN Prospective study. OBJECTIVE To evaluate the functional outcome of two-stage anterior and posterior instrumented fusion without fixation to the sacrum on 11 patients with neuromuscular scoliosis from thoracolumbar myelomeningocele. SUMMARY OF BACKGROUND DATA To our knowledge, there are no published results of combined anterior and posterior(More)
INTRODUCTION There is a controversial discussion about the adequate surgical procedure for degenerative lumbar spinal stenosis. Due to the observation that the degenerative lumbar spinal stenosis takes place predominantly at the interlaminar region on the level of the disc involving facets and bulging of the ligamentum flavum, resection of the whole lamina(More)
AIM Different systems are used for total knee arthroplasty (TKA). Compared were a press-fit femur condyle replacement system with fixed tibial PE-inlay versus a rotating tibia component system with an emphasis on the early functional results. METHOD Patient selection and the use of the Knee Society Score for this randomized and prospective study were(More)
Eine Möglichkeit der Reparation von Knorpelläsionen am Kniegelenk stellt die autologe Knorpel-Knochen-Transplantation dar. So gelingt es, hyalinen Knorpel an den Ort des Defekts zu bringen. Je nach Defektgröße und -lokalisation kann die Transplantation arthroskopisch erfolgen. An der Orthopädischen Universitätsklinik Düsseldorf wurden in den letzten 24(More)
Only one treatise devoted to medical history taking (anamnesis) has come down to us from antiquity: Medical questions by Rufus Ephesius (from about 80 to about 150 AD). The work was rediscovered, published and translated from Greek into French by Daremberg and Ruelle in the 19th century. The word 'anamnesis' for history taking only came into use halfway(More)