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Providing efficient data aggregation while preserving data privacy is a challenging problem in wireless sensor networks research. In this paper, we present two privacy-preserving data aggregation schemes for additive aggregation functions. The first scheme -cluster-based private data aggregation (CPDA)-leverages clustering protocol and algebraic properties(More)
Many stem cells (SCs) respond to Wnt signaling, but whether beta-catenin's DNA binding partners, the Tcfs, play a role in SCs in the absence of Wnts, is unknown. In adult skin, quiescent multipotent progenitors express Tcf3 and commit to a hair cell fate in response to Wnt signaling. We find that embryonic skin progenitors also express Tcf3. Using an(More)
Data aggregation is an efficient mechanism widely used in wireless sensor networks (WSN) to collect statistics about data of interests. However, the shared-medium nature of communication makes the WSNs are vulnerable to eavesdropping and packet tampering/injection by adversaries. Hence, how to protect data privacy and data integrity are two major challenges(More)
Upon exposure to stress, tRNAs are enzymatically cleaved, yielding distinct classes of tRNA-derived fragments (tRFs), yielding distinct classes of tRFs. We identify a novel class of tRFs derived from tRNA(Glu), tRNA(Asp), tRNA(Gly), and tRNA(Tyr) that, upon induction, suppress the stability of multiple oncogenic transcripts in breast cancer cells by(More)
Providing efficient data aggregation while preserving data privacy is a challenging problem in wireless sensor networks research. In this article, we present two privacy-preserving data aggregation schemes for additive aggregation functions, which can be extended to approximate MAX/MIN aggregation functions. The first scheme---<i>Cluster-based Private Data(More)
Single-layered embryonic skin either stratifies to form epidermis or responds to Wnt signaling (stabilized beta-catenin) to form hair follicles. Postnatally, stem cells continue to differentially use Wnt signaling in long-term tissue homeostasis. We have discovered that embryonic progenitor cells and postnatal hair follicle stem cells coexpress Tcf3 and(More)
The canonical Wnt/β-catenin signaling pathway classically functions through the activation of target genes by Tcf/Lef-β-catenin complexes. In contrast to β-catenin-dependent functions described for Tcf1, Tcf4 and Lef1, the known embryonic functions for Tcf3 in mice, frogs and fish are consistent with β-catenin-independent repressor activity. In this study,(More)
Data fusion or information collection is one of the fundamental functions in the future cyber-physical systems. But, privacy concerns must be addressed and security must be assured in such systems. It is very challenging to achieve the synergy of privacy and integrity, because privacy preserving schemes try to hide or interfere with data, while integrity(More)
BACKGROUND Focal Dermal Hypoplasia (FDH) is a genetic disorder characterized by developmental defects in skin, skeleton and ectodermal appendages. FDH is caused by dominant loss-of-function mutations in X-linked PORCN. PORCN orthologues in Drosophila and mice encode endoplasmic reticulum proteins required for secretion and function of Wnt proteins. Wnt(More)