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Young rats exposed to peppermint odor and reinforcing tactile stimulation from postnatal days (PND) 1-18 increase their preference for that odor relative to controls. This early olfactory memory is accompanied by an 80% increase in the density of glomerular-layer cells displaying Fos-like immunoreactivity in response to the learned odor on PND 19. The(More)
 Fischer 344 (F344) rats are reportedly 75-fold more sensitive than Sprague Dawley (S-D) rats to 1,2-dichlorobenzene (o-DCB) hepatotoxicity. Lethality studies were conducted since no information was available regarding the ultimate consequence of this sensitivity in terms of animal survival in the two strains. LD50s for o-DCB (1.66 ml/kg and 1.76 ml/kg in(More)
In the presence of extracellular Ca2+ (Cao), isolated preparations of rabbit aortas (RA) and epicardial porcine coronary arteries (PCA) contracted dose-dependently to the cumulative addition of NaF (2.5-12 mmol/l); the EC50 values were resp. 6.87 +/- 0.25 (n = 6) and 6.35 +/- 0.42 (n = 11) mmol/l. In Cao-free EGTA-containing solution, the vessel(More)
A moderate elevation of external (K 0 + ) (5–10 mM) induces relaxation in bovine facial and human saphenous veins. A further increase of (K 0 + ) leads to biphasic reactions (relaxation followed by contraction). Concentrations of (K 0 + ) higher than about 15 mM cause contractions only. The potassium-induced relaxation may be explained by the stimulation of(More)
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