Learn More
We propose a new cluster-based semantic similarity/distance measure for the biomedical domain within the framework of UMLS. The proposed measure is based mainly on the cross-modified path length feature between the concept nodes, and two new features: (1) the common specificity of two concept nodes, and (2) the local granularity of the clusters. We also(More)
—Most of the intelligent knowledge-based applications contain components for measuring semantic similarity between terms. Many of the existing semantic similarity measures that use ontology structure as their primary source cannot measure semantic similarity between terms and concepts using multiple ontologies. This research explores a new way to measure(More)
The production of pectin lyase (Pnl) and carotovoricin (Ctv), as well as cell lysis in the plant-pathogenic bacterium Erwinia carotovora subsp. carotovora Er are induced by mitomycin C. Here, Pnl and Ctv production and cell lysis were found to be temperature-dependent. The optimal temperature for Pnl production was 30 degrees C. However, the optimal(More)
The semantic similarity techniques are interested in determining how much two concepts, or terms, are similar according to a given ontology. This paper proposes a method for measuring semantic similarity/distance between terms. The measure combines strengths and complements weaknesses of existing measures that use ontology as primary source. The proposed(More)
Carotovoricin Er (CtvEr), which is produced by a plant soft rot disease causative agent, Erwinia carotovora subsp. carotovora Er, is a high-molecular-weight bacteriocin showing Myoviridae phage-tail-like morphology with contractile sheath and plural tail fibers. We determined the complete nucleotide sequences of CtvEr genes on the E. carotovora Er(More)
Carriers of drugs in cancer therapy are required to reduce side-effects of the drugs to normal cells. Here we constructed killed recombinant Bacillus subtilis spores (SA1) that expressed streptavidin as a chimeric fusion to the spore coat protein CotB and used the spores as bioparticle carrier. When bound with biotinylated cetuximab these spores could(More)
We present a cross-cluster approach for measuring the semantic similarity/distance between two concept nodes in ontology. The proposed approach helps overcome the differences of granularity degrees of clusters in ontology that most ontology-based measures do not concern. The approach is based on 3 features (1) cross-modified path length feature between the(More)
This paper presents a cross-ontology approach, as an extension of the Cluster-Based approach, to measure semantic distance between concepts within single ontology or between concepts dispersed in multiple ontologies in a unified framework in the biomedical domain. The experimental results (with ~0.81 correlation with human scores) confirmed that the(More)
  • 1