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Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening.
Fonsecin B has been identified as stabilizing ligand of c-myc G-quadruplex DNA using high-throughput virtual screening of a natural product database, and inhibited Taq polymerase-mediated DNA
Structure-based discovery of natural-product-like TNF-α inhibitors.
TLDR
Two natural-product-like inhibitors of tumor necrosis factor (TNF-α) have been identified using structure-based virtual screening, and display potency comparable to that of the strongest TNF- α inhibitor reported to date.
A selective oligonucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution.
An oligonucleotide-based luminescent platinum(II) switch-on probe has been developed for selective detection of nanomolar Hg(2+) ions.
CCQM-K131 Low-polarity analytes in a multicomponent organic solution: polycyclic aromatic hydrocarbons (PAHs) in acetonitrile
Solutions of organic analytes of known mass fraction are typically used to calibrate the measurement processes used to determine these compounds in matrix samples. Appropriate value assignments and