Ho-Suck Oh

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PURPOSE Gastric cancer is one of the most prevalent cancers worldwide. 5-fluorouracil (5-FU) and cisplatin are the most commonly used drugs for the treatment of gastric cancer. However, a significant number of tumors often fail to respond to chemotherapy. MATERIALS AND METHODS To better understand the molecular mechanisms underlying drug resistance in(More)
BACKGROUND Capecitabine plus oxaliplatin (XELOX) is considered one of the primary chemotherapy regimens for patients with metastatic colorectal cancer (CRC). Oxaliplatin plus S-1 (OS) has also demonstrated significant efficacy in CRC. We performed this randomized phase II study to evaluate the efficacy and toxicity of XELOX versus OS as first-line(More)
P urpose: To eva luate the e fficacy and toxicity of heptapla tin, paclitaxe l, and 5 -fluorouracil combination chemotherapy in patients with advanced gastric cancer. M ateria ls and M ethods: Between July 2002 and S eptember 2003 , nineteen patients were enrolled in this study. P aclitaxe l 135 mg/m 2 iv on day 1 , heptapla tin 400 mg/m 2 iv on day 2 and 5(More)
PURPOSE To evaluate the efficacy and toxicity of heptaplatin, paclitaxel, and 5-fluorouracil combination chemotherapy in patients with advanced gastric cancer. MATERIALS AND METHODS Between July 2002 and September 2003, nineteen patients were enrolled in this study. Paclitaxel 135 mg/m(2) iv on day 1, heptaplatin 400 mg/m(2) iv on day 2 and 5-fluorouracil(More)
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