Hitoshi Tanabe

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In healthy humans, the two cerebral hemispheres show functional specialization to a degree unmatched in other animals, and such strong hemispheric specialization contributes to unimanual skill acquisition [1, 2]. When most humans learn a new motor skill with one hand, this process results in performance improvements in the opposite hand as well [3-6].(More)
Intravenous norepinephrine infusion test was performed in eight patients with amyotrophic lateral sclerosis (ALS) supported by respirators and nine control subjects, to examine α-adrenoceptor function of peripheral resistant blood vessels. Baseline plasma norepinephrine concentrations in ALS patients were significantly higher than those in control subjects,(More)
Electrical impedance tomography (EIT) is a noninvasive technique used to assess regional gas distribution in the lung. We experienced a patient with acute cor pulmonale during high positive-pressure ventilation for the treatment of severe acute respiratory distress syndrome. Prone positioning was beneficial for unloading the right ventricle for treatment of(More)
Blood pressure changes in response to intravenous drug administration were examined in a respirator-dependent 49-year-old patient with sporadic amyotrophic lateral sclerosis (ALS) who developed severe hypertensive attacks. She showed severe hypertension and tachycardia during the daytime and nocturnal hypotension without compensatory tachycardia, which were(More)
Our case, comparable to the one reported by Urich and Wilkinson [8], is an additional typical example of the disorder. There is no evidencc of a vascular or toxic origin of the muscle necrosis. Thus, in accordance with earlier case reports, the condition may be classified as a paraneoplastic myopathy. The pathogenesis remains obscure; there is no evidence(More)
A 65-year-old man with familial amyotrophic lateral sclerosis (ALS) with posterior column involvement showed fairly slow progression of the illness and lived with the aid of a respirator for 12 years. Neuropathological examinations showed simultaneous involvement of the pyramidal tract and lower motor neurons as well as degeneration in the Clarke’s nucleus-(More)
When recording the activity of the posterior cricoarytenoid muscle (PCA) with surface electrodes, there is contamination from the surrounding muscles such as the cricopharyngeal muscle. We therefore devised a new oesophageal catheter electrode of the separate type, having three individual surface electrodes for the PCA, cricopharyngeal muscle and diaphragm.(More)
1. Mit der Koelleschen Methode wurde histochemisch die Cholinesterase-Aktivität in zahlreichen nervösen Formationen des Menschen (zum Teil auch bei Pferd und Hund) untersucht. 2. In denMeissnerschen Körperchen, Vater-Pacinischen Körperchen, Geschlechtskörperchen und Geschmacksknospen fand sich reichlich ChE. 3. In Tränendrüsen, Speicheldrüsen,(More)
Sirs: The muscles involved in the Duchenne type of muscular dystrophy (DMD) are predominantly proximal but, as the disease progresses, become generalized. The patient's death usually occurs before the 20th year, most often due to respiratory complications. The ability to defecate remains normal until the terminal stage [3]. Computed tomography (CT) of(More)