Milan Seth3
Pascal Meier2
Ingrid L. Bergin1
Jeptha P. Curtis1
3Milan Seth
2Pascal Meier
1Ingrid L. Bergin
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Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis affecting 5 million adults in the United States, with an age-adjusted prevalence of 4% to 15% and increasing up to 30% with age and the presence of cardiovascular risk factors. In this article we focus on lower extremity PAD and specifically on the superficial femoral and(More)
BACKGROUND Contrast-induced nephropathy is the leading cause of in-hospital acute renal failure. This side effect of contrast agents leads to increased morbidity, mortality, and health costs. Ensuring adequate hydration prior to contrast exposure is highly effective at preventing this complication, although the optimal hydration strategy to prevent(More)
BACKGROUND The Thrombolysis in Myocardial Infarction (TIMI) risk scores for Unstable Angina/Non-ST-elevation myocardial infarction (UA/NSTEMI) and ST-elevation myocardial infarction (STEMI) and the Global Registry of Acute Coronary Events (GRACE) risk scores for in-hospital and 6-month mortality are established tools for assessing risk in Acute Coronary(More)
Contrast-induced acute kidney injury (CIAKI) is one of the commonest complications associated with contrast media (CM). Although the exact etiology of CIAKI remains unclear, one hypothesis involves vasoconstriction of afferent arterioles resulting in renal ischemia. Increased renal blood flow, therefore, might represent an attractive target for the(More)
To cite: Sinha SS, Gurm HS. The double jeopardy of chronic obstructive pulmonary disease and myocardial infarction. Despite several therapeutic advances in the last few decades, chronic obstructive pulmonary disease (COPD) is a burgeoning cause of morbidity and mortality worldwide and is the fourth leading cause of death globally. 1 Yet a curious paradox(More)
To the Editor: Door-to-balloon time (DTB) is the focus of national guidelines, and intense efforts to reduce it have been a core component of many national quality improvement campaigns. Recently, it has been the high point of advertisement campaigns by hospital systems and ultimately might be used to reward performance by payers. It is now publicly(More)
  • Michael P. Thomas, Craig S. Parzynski, Jeptha P. Curtis, Milan Seth, Brahmajee K. Nallamothu, Paul S. Chan +5 others
  • 2015
BACKGROUND Substantial geographic variation exists in percutaneous coronary intervention (PCI) use across the United States. It is unclear the extent to which high PCI utilization can be explained by PCI for inappropriate indications. The objective of this study was to examine the relationship between PCI rates across regional healthcare markets utilizing(More)
BACKGROUND Prior research has shown a transient increase in the incidence of acute myocardial infarction (AMI) after daylight savings time (DST) in the spring as well as a decrease in AMI after returning to standard time in the fall. These findings have not been verified in a broader population and if extant, may have significant public health and policy(More)
BACKGROUND Prior studies have proposed to restrict the contrast volume (CV) to <3x calculated creatinine clearance (CCC), to prevent contrast induced nephropathy (CIN) post percutaneous coronary interventions (PCI). The predictive value of this algorithm for CIN and therefore the benefit of this approach in high risk patients has been questioned. The aim of(More)
OBJECTIVE To explore the feasibility of a novel approach using an augmented one-class learning algorithm to model in-laboratory complications of percutaneous coronary intervention (PCI). MATERIALS AND METHODS Data from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) multicenter registry for the years 2007 and 2008 (n=41 016) were(More)