Hisazumi Ikeda

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Podoplanin, a type I transmembrane glycoprotein with an effect of platelet aggregation, has been reported to be one of the possible prognostic factors of oral squamous cell carcinoma (OSCC). However, the biological significance of podoplanin is largely unclear. The aim of this study was to develop a practical model for the prediction of prognosis using the(More)
Locoregional recurrence of oral tongue squamous cell carcinoma (OTSCC) has been considered a poor prognostic entity in terms of survival rate. The purpose of this study was to evaluate the incidence of locoregional recurrence and to identify significant risk factors for locoregional recurrence in early-stage OTSCC. We retrospectively reviewed the records of(More)
OBJECTIVES The purpose of this study is to analyze the morphological change of cell nuclei and the change of proliferating activity of oral malignancy and epithelial dysplasia between before and after photodynamic therapy in order to predict recurrence. MATERIAL AND METHODS We experienced 14 cases of oral squamous cell carcinoma, one case of verrucous(More)
The aim of the present study was to elucidate the associations between the expression of the vascular endothelial growth factor-C (VEGF-C)/VEGF receptor-3 (VEGFR-3) axis and lymphangiogenesis, regional lymph node metastasis and clinicopathological factors in oral tongue squamous cell carci-noma (OTSCC) using immunohistochemistry. The expression of VEGF-C,(More)
Purpose Myocutaneous flaps were commonly used to repair the mucosal defect that results from ablative tumor surgery. However, skin is not a perfect substitute for the oral mucosa because it can lead to poor hygiene due to hair growth and desquamation. The myodermal flaps used for the reconstruction of mucosa in oncologic surgery of the oral cavity. Material(More)
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