Hisashi Yoshioka

Learn More
About a half of the antierythrocyte autoantibody transgenic (autoAb Tg) mice, in which almost all B cells are detected in the spleen, lymph nodes, and Peyer's patches, but not in the peritoneal cavity, suffer from autoimmune hemolytic anemia. The occurrence of this disease is strongly linked to production of autoAb by activated peritoneal B-1 cells in the(More)
Single mitochondria show the spontaneous fluctuations of DeltaPsim. In this study, to examine the mechanism of the fluctuations, we observed DeltaPsim in single isolated heart mitochondria using time-resolved fluorescence microscopy. Addition of malate, succinate, or ascorbate plus TMPD to mitochondria induced polarization of the inner membrane followed by(More)
Morphological features of iris fibroblasts in the dilator muscle region of the Japanese monkey iris were demonstrated by transmission and scanning electron microscopy. The iris fibroblasts in the dilator muscle region formed the boundary between the dilator muscle and the iris stroma. These iris fibroblasts were characteristically accompanied by numerous(More)
The innervation of the trabecular meshwork of the anterior chamber angle in monkey eyes was studied by transmission and scanning electron microscopy. According to the transmission electron microscopic examination, the nerve terminals in the trabecular meshwork mostly contained dense core vesicles after treatment with 5-hydroxydopamine and thus were(More)
Unilateral removal of the superior cervical ganglion was performed in the pigmented rabbit. Degenerative axons which were presumed to be adrenergic were observed postoperatively in the denervated choroid. At 2-3 months after the operation, there was evidence of degeneration of the choroidal melanocytes on the denervated side. Choroidal melanocytes contained(More)
The trabecular meshwork surface in the Japanese monkey eye was observed by scanning electron microscopy. Many varicose nerve fibers were recognized in the anterior surface of the trabecular sheets and in the intertrabecular space facing the anterior chamber. The nerve fibers often branched and thus formed a loose-meshed plexus. These varicose nerve fibers(More)
The innervation of the choroidal melanocytes of the rabbit was studied by transmission electron microscopy with the aid of 5-hydroxydopamine treatment. Three types of nerve terminals, which were classified as adrenergic, cholinergic, and non-adrenergic/non-cholinergic (NANC), were recognized in relation to melanocytes in the choroid. Morphologically, the(More)
  • 1