Hisashi Watanabe

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Psychopathological investigation was conducted on the basis of the clinical observation of 23 subjects whose cenesthopathic symptoms began before 30 years of age. This illness is called 'adolescent cenesthopathy' based on the specificity of this mental condition to the adolescent period. Adolescent cenesthopathy is compared to schizophrenia,(More)
BACKGROUND The relationship of saliva with plasma protein levels makes saliva an attractive diagnostic tool. Plasma levels of adiponectin and leptin in healthy individuals or diabetes mellitus patients have been previously reported. Nevertheless, salivary levels of these adipocytokines in patients with metabolic syndrome (MS) have never been investigated.(More)
In treating patients with severe anorexia nervosa, it is important to improve their physical condition first. Patients who had lost close to 60% standard bodyweight (SBW) were candidates for inpatient treatment due to the mortality risk. With 80% SBW as the target for therapy, they were given both intravenous hyperalimentation and food by oral intake in(More)
Human beta-defensin-3 (HBD-3) has versatile antibacterial activity against oral bacteria and can promote the proliferation of fibroblasts. The goal of the present study was to investigate the effect of HBD-3 on attachment and proliferation of periodontal ligament cells (PDL) onto the periodontitis affected root surfaces. PDL cells were seeded onto healthy(More)
BioScience Trends is one of a series of peer-reviewed journals of the International Research and Cooperation BioScience Trends devotes to publishing the latest and most exciting advances in scientific research. Articles cover fields of life science such as biochemistry, molecular biology, clinical research, public health, medical care system, and social(More)
It is a common philosophical question as to whether your blue is the same as my blue. The two-tone striped dress shown in Figure 1, which attracted a lot of attention on the Internet, gave us a clear answer: "No." Some people see the dress as blue and black, whereas others insist it's white and gold. So your blue can be my white. Why is it that people(More)
Background: Our previous microarray study showed that sevoflurane anesthesia affects the expression of rat genes in multiple organs including the liver. In this study, we investigated whether liver protein expression was altered after propofol, sevoflurane, or isoflurane anesthesia. We also investigated differences in the time course of each drug 24 and 72(More)
BioScience Trends is one of a series of peer-reviewed journals of the International Research and Cooperation BioScience Trends devotes to publishing the latest and most exciting advances in scientific research. Articles cover fields of life science such as biochemistry, molecular biology, clinical research, public health, medical care system, and social(More)
The problem of 'social withdrawal' among young adults is the focus of considerable attention in Japan today. Among the various manifestations of social withdrawal, a 'primary social withdrawal' group has been identified that cannot be diagnosed by the established classification of mental disorders. In an earlier report it was suggested that the onset(More)
Mass fragmentography was used for quantitation of apomorphine in whole rat brain. Following extraction with 0.45 N perchloric acid, the components were derivatized to the O,O-bis(trimethylsilyl) (TMS) derivatives with N,O-bis(trimethylsilyl)trifluoroacetamide at 30 degrees C. The molecular ions of the TMS derivatives of apomorphine (m/z 411) and(More)