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  • Toshifumi Nomura, Aileen Sandilands, +11 authors Hiroshi Shimizu
  • Biology, Medicine
  • The Journal of allergy and clinical immunology
  • 2007 (First Publication: 1 February 2007)
  • BACKGROUND Filaggrin is a key protein involved in skin barrier function. Recently, mutations in the filaggrin gene, FLG, were identified in European families with ichthyosis vulgaris (IV) and shownExpand
  • Hisashi Sugiura, Hayao Ebise, +5 authors Takeshi Kimura
  • Medicine, Biology
  • The British journal of dermatology
  • 2005
  • BACKGROUND Atopic dermatitis (AD)-specific genes have not yet been clarified. Objectives To identify gene expression specific to active atopic skin lesions. METHODS We analysed 23,000 genes in skinExpand
  • Hisashi Sugiura, Naoka Umemoto, +7 authors Masami Uehara
  • Medicine
  • Acta dermato-venereologica
  • 1998 (First Publication: 21 July 1998)
  • To ascertain the prevalence of childhood and adolescent atopic dermatitis in a Japanese population, we clinically observed the total body of 5 to 6-year-old children (994 cases), 7 to 9-year-oldExpand
  • Keiko Tanaka, Michael H. Roberts, Naokatsu Yamamoto, Hisashi Sugiura, Masami Uehara, Julian M. Hopkin
  • Medicine, Biology
  • International journal of immunogenetics
  • 2006 (First Publication: 1 December 2006)
  • It has been reported that a functional polymorphism in the promoter of the RANTES gene (-403G/A) is associated with atopic dermatitis in a German population. Although there are several reports on theExpand