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- Sho-ichi Yamagishi, Hisashi Adachi, +9 authors Tsutomu Imaizumi
- The Journal of clinical endocrinology and…
- 2006
CONTEXT
Pigment epithelium-derived factor (PEDF), a potent inhibitor of angiogenesis with neuronal differentiating activity, inhibits endothelial cell injury in vitro, thus suggesting the involvement… (More)
BACKGROUND AND PURPOSE
We examined whether hyperhomocysteinemia is an independent risk factor for increased carotid artery intimal-medial wall thickness (IMT) in a large, randomly selected community… (More)
- Etsuko Ikeda, Kiyohito Yagi, +13 authors Hajime Ohgushi
- Differentiation; research in biological diversity
- 2008
Adult stem cells have been reported to exist in various tissues. The isolation of high-quality human stem cells that can be used for regeneration of fatal deseases from accessible resources is an… (More)
- Akiko Hiratsuka, Hisashi Adachi, +7 authors Tsutomu Imaizumi
- The Journal of clinical endocrinology and…
- 2005
Hepatocyte growth factor (HGF) is one of the adipocytokines. We evaluated whether serum levels of HGF are related to the metabolic syndrome. A total of 1474 subjects of a general population free of… (More)
- David R. Jacobs, Hisashi Adachi, +4 authors George L. Blackburn
- Archives of internal medicine
- 1999
BACKGROUND
Although most observations in the Seven Countries Study suggest that cigarette smoking is harmful for health, universality of this conclusion remains controversial.
SUBJECTS AND METHODS… (More)
- Shigeyuki Nagaoka, Takafumi Yoshida, +11 authors Michio Sata
- Liver international : official journal of the…
- 2007
BACKGROUND/AIMS
C-reactive protein (CRP) was recently identified as a prognostic factor for patients with hepatocellular carcinoma (HCC) after surgical resection. We investigated the relationship… (More)
- Kazuo Nakamura, Sho-ichi Yamagishi, +5 authors Tsutomu Imaizumi
- Microvascular research
- 2008
We have recently found that soluble form of receptor for advanced glycation end products (sRAGE) levels are positively associated with inflammatory biomarkers and the presence of coronary artery… (More)
- Alessandro Menotti, George L. Blackburn, Daan Kromhout, Aulikki Nissinen, Hisashi Adachi, Mariapaola Lanti
- European Journal of Epidemiology
- 2001
This analysis aims at describing all-cause mortality and their determinants in 16 cohorts of middle-aged men of eight nations. A total of 12,763 men aged 40–59 years were enrolled in the late 1950s… (More)
- Erik J Giltay, Frans G Zitman, +5 authors Daan Kromhout
- Journal of affective disorders
- 2010
BACKGROUND
Prospective cohort studies on biological risk factors of completed suicide are scarce. We aimed to test which biological risk factors independently identify subjects at increased risk of… (More)
- Sho-ichi Yamagishi, Hisashi Adachi, +9 authors Tsutomu Imaizumi
- Metabolism: clinical and experimental
- 2006
The advanced glycation end products (AGEs)-receptor for AGE (RAGE) axis is implicated in diabetic vascular complications. Administration of soluble form of RAGE (sRAGE) to mice has been shown to… (More)