Hisanori Kanazawa

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BACKGROUND/OBJECTIVES Pericardial fat (PF) and complex fractionated atrial electrogram (CFAE) are both associated with atrial fibrillation (AF). Therefore, we examined the relation between PF and CFAE area in AF. METHODS The study population included 120 control patients without AF and 120 patients with AF (80 paroxysmal AF and 40 persistent AF) who(More)
Complex fractionated atrial electrogram (CFAE) has been suggested to contribute to the maintenance of atrial fibrillation (AF). However, electrophysiologic characteristics of the left atrial myocardium responsible for genesis of CFAE have not been clarified. Non-contact mapping of the left atrium was performed at 37 AF onset episodes in 24 AF patients.(More)
BACKGROUND Non-vitamin K antagonist oral anticoagulants are used to prevent thromboembolism in patients with atrial fibrillation. The T-TAS "Total Thrombus-formation Analysis System" (Fujimori Kogyo Co Ltd) was developed for quantitative analysis of thrombus formation using microchips with thrombogenic surfaces (collagen, platelet chip [PL] ; collagen plus(More)
BACKGROUND The complex fractionated atrial electrogram (CFAE) region has been suggested to contribute to the maintenance of atrial fibrillation (AF), but its role for the initiation of AF has not been clarified. OBJECTIVE We analyzed the mechanisms of the initiation of random reentrant wave propagation at AF onset, especially in relation to CFAE region.(More)
BACKGROUND Oxidative stress is considered to contribute to the pathological consequences of atrial fibrillation (AF). We examined the level of oxidative stress in AF patients and changes in its level following sinus rhythm restoration. METHODS Oxidative stress level was evaluated by urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of oxidative(More)
BACKGROUND Increased resting heart rate (HR) due to sympathetic hyperactivity is associated with coronary risk factors and increased cardiovascular events. Acute myocardial infarction (AMI) is accompanied by autonomic imbalance, which is characterized by sympathetic activation and parasympathetic inactivation. Although an increased HR in patients with acute(More)
The mechanism and tachycardia circuit of verapamil-sensitive atrial tachycardia originating from the atrioventricular annulus (AVA-AT) other than the atrioventricular node vicinity are not well clarified. In 23 patients, we examined the mechanism and anatomic tachycardia circuit of AVA-AT. While recording the atrial electrogram at the earliest atrial(More)
BACKGROUND The anatomical location of the reentry circuit in verapamil-sensitive atrial tachycardia originating from the vicinity of atrioventricular node (V-AT) is not well clarified. OBJECTIVE To define the reentry circuit of V-AT. METHODS In 17 patients with V-AT, rapid atrial pacing at a rate 5 beats/min faster than the tachycardia rate was(More)
BACKGROUND Although vein stenting is popular for treatment for venous thromboembolism due to mechanical compression, some cases are forced to avoid inserting align agents because of immunodeficiency. CASE PRESENTATION An 82-year-old man with left extremity redness and swelling presented to a hospital for a medical evaluation. The patient was(More)
BACKGROUND It remains unclear whether atrial fibrillation (AF) is maintained by the rotor. OBJECTIVE We evaluated the role of the rotor and examined its mechanism. METHODS Among 75 patients with AF (60 paroxysmal, 15 persistent AF) who underwent 3-dimensional noncontact left atrial mapping during AF, we examined the prevalence and location of rotor(More)