Hisakazu Shindo

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Menstruation in primates is preceded by a period of intense vasoconstriction, with resultant ischemia-reperfusion. Although apoptosis is involved in endometrial breakdown, the relationship between ischemia-reperfusion and apoptosis in the female genital tract has not been determined. To investigate the relationship between ischemia-reperfusion and apoptosis(More)
To achieve complete ablation of liver cancer in the hepatic dome, thoracoscopy-assisted radiofrequency ablation was attempted in three patients. Under general anesthesia and left lateral position, a thoracoport site was placed in the 6th intercostal space and a small thoracotomy was placed in the 7th intercostal space. In all three cases, the liver cancer(More)
BACKGROUND/AIMS Thoracoabdominal approach might be safe and facilitate hepatic resection for tumors located in the right lobe. To evaluate the clinical usefulness of the thoracoabdominal approach using oblique incision for the right-side hepatectomy, we compared the perioperative data with those of the abdominal approach. METHODOLOGY The oblique incision(More)
BACKGROUND alpha-Fetoprotein (AFP) has been used as a marker for hepatocellular carcinoma (HCC). However, AFP levels are often high in patients with chronic hepatitis or cirrhosis. Protein-induced vitamin K absence or antagonist II (PIVKA-II) is more sensitive for the diagnosis of HCC and prediction of patient survival. Changes in these markers after(More)
BACKGROUND/AIMS The relative advantages of pancreaticojejunostomy and pancreaticogastrostomy after pancreaticoduodenectomy remain to be established. To clarify differences between the two procedures, we examined 66 patients who underwent PD and compared clinical and histological parameters, surgical records and patient outcomes. METHODOLOGY In this(More)
Interferon regulatory factor (IRF)-4 is a member of the IRF transcription factor family, whose expression is primarily restricted to lymphoid and myeloid cells. In T-cells, IRF-4 expression is induced by T-cell receptor (TCR) cross-linking or treatment with phorbol-12-myristate-13-acetate (PMA)/Ionomycin, and IRF-4 is thought to be a critical factor for(More)
A new insulin sensitivity index was devised on the basis of an autoregressive model and its validity was investigated. Using data from the 75-g oral glucose tolerance test (OGTT), 115 subjects were divided into 3 groups: 40 with normal glucose tolerance, 34 with impaired glucose tolerance, and 41 with type 2 diabetes mellitus. The new insulin sensitivity(More)
Title Interferon regulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel. Author(s) Shindo, Hisakazu; Yasui, Kiyoshi; Yamamoto, Kazuo; Honma, Kiri; Yui, Katsuyuki; Kohno, Tomoko; Ma, Yuhua; Chua, Koon Jiew; Kubo, Yoshinao; Aihara, Hitoshi; Ito, Takashi; Nagayasu, Takeshi; Matsuyama, Toshifumi; Hayashi, Hideki Citation Cytokine,(More)
Title Surgical Strategy for Low Imperforate Anus in Girls -Cutback Anoplasty , Anal Transplantation or Limited Posterior Sagittal Anorectoplasty?Author(s) Obatake, Masayuki; Yamashita, Hideki; Shindo, Hisakazu; Sumida, Norihisa; Nakagoe, Tohru Citation Acta medica Nagasakiensia. 2003, 48(1-2), p.51-54 Issue Date 2003-06-25 URL(More)
BACKGROUND Fine-needle aspiration cytology (FNAC) is a challenging and risky procedure for inexperienced clinicians to perform because of the proximity of the thyroid to the jugular veins, carotid arteries, and trachea. A phantom model for transfixion practice would help train clinicians in FNAC. OBJECTIVE To fabricate a tailored phantom with(More)