Hiroyuki Yasuo

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The tadpole larva of an ascidian develops 40 notochord cells in the center of its tail. Most of the notochord cells originate from the A-line precursors, among which inductive interactions are required for the subsequent differentiation of notochord. The presumptive-endoderm blastomeres or presumptive-notochord blastomeres themselves are inducers of(More)
The notochord is one of the characteristic features of the phylum Chordata. The vertebrate Brachyury gene is known to be essential for the terminal differentiation of chordamesoderm into notochord. In the ascidian, which belongs to the subphylum Urochordata, differentiation of notochord cells is induced at the late phase of the 32-cell stage through(More)
Chordates are thought to have emerged from some common ancestor of deuterostomes by organizing shared anatomical and embryological features including a notochord, a dorsal nerve cord and pharyngeal gill slits. Because the notochord is the most prominent feature of chordates and because the Brachyury (T) gene is essential for notochord formation, the T gene(More)
Antibody subclasses directed against the core protein (HCc) of hepatitis C virus (HCV) were measured in 27 patients with acute non-A, non-B (NANB) hepatitis, and 99 patients with chronic HCV-associated liver disease. IgM, IgA, and IgG anti-HCc responses were observed in 11 (40.7%), 7 (25.9%), and 18 (67%) patients with acute NANB hepatitis, respectively.(More)
The vertebrate Brachyury (T) gene is transiently expressed in nascent and migrating mesoderm, in the differentiating notochord, and in the tail bud, reflecting its independent functions. In contrast, the expression of an ascidian Brachyury gene (As-T) is restricted to differentiating notochord. The present study revealed that the genome of Halocynthia(More)
Mucoprotein (here inaf ter called MP), protein bound polysaccharide (PBP). Mucoprotein bound polysaccharide (PmP). Diphenylamine reactive substance (DPA), /~-lipoprotein and C-reactive protein (CRP) were determined in sera of pat ients who were suffered f rom gast r ic cancer (67 cases) and o ther gas t r ic diseases (33 cases) before and af te r operation.(More)
Often t imes, we surgeons confront the perplexing postoperat ive complications such as posts ternal pain, regurgi ta t ion of the content of the s tomach into oesophagus and vomiting, af ter the per formance of resection of gas t r ic fundus for the t r ea tmen t of the cancer of cardia or a lower par t of an oesophagus and a f t e r the resection of the(More)
The role of reserved pyloric sphincter as the causative factor of esophagitis was surveyed. The clinical s tat ist ics of operated cases with cancer of lower par t of esophagus or cardia revealed that the regurgitative esophagitis occurs on the average a month after operation and that pyloroplasty is an effective mean to prevent the esophagitis.(More)
Peritoneography with "CONRAY" is applied for the diagnosis of intraabdominal tumors. Conray of 30 to 40cc (different amount, depending upon cases) is infused into the abdominal cavity through polyethylene tube of 1.2 mm in external diameter which is put into the cavity with a needle. Upper abdominal organs, ex. stomach, cardia, liver, gallbladder, pancreas,(More)