Hiroyo Hotta

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POU class V (POU-V) transcription factors play the important role in maintenance of pluripotency and cell differentiation. Pou5f3.2 (Oct25), one of Xenopus POU-V transcription factors, shows the zygotic expression prior to gastrulation. In order to know the molecular mechanism of pou5f3.2 expression at gastrula stage, we examined a responsiveness of(More)
Maternal mARNs are key players of the first steps of development in vertebrates. Initially silenced in oocytes, these transcripts are activated and translated after fertilization and play crucial roles in early cell lineage allocation into the germ layers. We previously reported that the RNA-binding protein XSeb4R regulates endoderm and mesoderm formation(More)
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