Hirotoshi Nakamura

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Essential role of GATA2 in the negative regulation of thyrotropin beta gene by thyroid hormone and its receptors.

Akio Matsushita, Shigekazu Sasaki, +6 authors Hirotoshi Nakamura
Molecular endocrinology
2007

Previously we reported that the negative regulation of the TSHbeta gene by T(3) and its receptor [thyroid hormone receptor (TR)] is observed in CV1 cells when GATA2 and Pit1 are introduced. Using… (More)

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

Yuhei Hotta, Hirotoshi Nakamura, +6 authors Nobuyuki Itoh
Endocrinology
2009

Fibroblast growth factors (Fgfs) are polypeptide growth factors with diverse functions. Fgf21, a unique member of the Fgf family, is expected to function as a metabolic regulator in an endocrine… (More)

Thyroid-hormone-dependent negative regulation of thyrotropin beta gene by thyroid hormone receptors: study with a new experimental system using CV1 cells.

Keiko Nakano, Akio Matsushita, +4 authors Hirotoshi Nakamura
The Biochemical journal
2004

The molecular mechanism involved in the liganded thyroid hormone receptor suppression of the TSHbeta (thyroid-stimulating hormone beta, or thyrotropin beta) gene transcription is undetermined. One of… (More)

Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gels.

Katsuyuki Nakajima, Takao Saito, +7 authors E. Doménech Campos
Clinica chimica acta; international journal of…
1993

We have developed a simple, rapid assay method for apo E-rich lipoproteins (d < 1.006 g/ml), using an immunoaffinity gel mixture of anti apo B-100 and apo A-I antibodies coupled to Sepharose 4B. The… (More)

Acute exacerbation of interstitial pneumonia associated with collagen vascular diseases.

Takafumi Suda, Yusuke Kaida, +11 authors Kingo Chida
Respiratory medicine
2009

BACKGROUND Acute exacerbation (AE) is currently established as a distinct condition with acute deterioration of respiratory status in idiopathic pulmonary fibrosis (IPF). Recently, several studies… (More)

Higher sensitivity and specificity for diffusion-weighted imaging of malignant lung lesions without apparent diffusion coefficient quantification.

Tomohiro Uto, Yasuo Takehara, +6 authors Kingo Chida
Radiology
2009

PURPOSE To compare the performance of apparent diffusion coefficient (ADC) with that of signal intensity of the lesion-to-spinal cord ratio (LSR) in differentiating lung cancer from benign lesions on… (More)

Mouse lung CD103+ and CD11bhigh dendritic cells preferentially induce distinct CD4+ T-cell responses.

Kazuki Furuhashi, Takafumi Suda, +9 authors Kingo Chida
American journal of respiratory cell and…
2012

Mouse lung dendritic cells (LDCs) have been recently shown to contain two major subpopulations: CD103(+) CD11b(low or negative) (CD103(+) LDCs) and CD103(-) CD11b(high) LDCs (CD11b(high) LDCs).… (More)

Introducing the reporting system for thyroid fine-needle aspiration cytology according to the new guidelines of the Japan Thyroid Association.

Kennichi Kakudo, Kaori Kameyama, Akira Miyauchi, Hirotoshi Nakamura
Endocrine journal
2014

The Japan Thyroid Association (JTA) recently published new guidelines for clinical management of thyroid nodules. This paper introduces their diagnostic system for reporting thyroid fine-needle… (More)

High expression of macrophage migration inhibitory factor in human melanoma cells and its role in tumor cell growth and angiogenesis.

Tomoko K Shimizu, Riichiro Abe, Hirotoshi Nakamura, Akira Ohkawara, Masashige Suzuki, Jun Nishihira
Biochemical and biophysical research…
1999

Macrophage migration inhibitory factor (MIF) is known to function as a cytokine, hormone, and glucocorticoid-induced immunoregulator. In this study, we reported for the first time that human… (More)

Differences in clinical features and prognosis of interstitial lung diseases between polymyositis and dermatomyositis.

Tomoyuki Fujisawa, Takafumi Suda, +12 authors Hirotoshi Nakamura
The Journal of rheumatology
2005

OBJECTIVE To assess the difference in clinical features and prognosis of patients with interstitial lung disease (ILD) comparing polymyositis (PM) and dermatomyositis (DM). METHODS Medical records… (More)

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