• Publications
  • Influence
Superoxide Generation in Directional Coronary Atherectomy Specimens of Patients With Angina Pectoris
Objective— NADH/NADPH oxidase is an important source of reactive oxygen species (ROS) in the vasculature. Recently, we demonstrated that p22phox, an essential component of this oxidase, was expressedExpand
  • 8
  • 3
Interaction of Oxidative Stress and Inflammatory Response in Coronary Plaque Instability
Objective— C-reactive protein (CRP), a predictor of cardiovascular events, localizes in atherosclerotic arteries and exerts proinflammatory effects on vascular cells. Reactive oxygen species (ROS)Expand
  • 10
  • 1
Endothelial NO Synthase Overexpression Inhibits Lesion Formation in Mouse Model of Vascular Remodeling
Abstract—NO produced by endothelial NO synthase (eNOS) plays important roles in the regulation of vascular tone and structure. The purpose of this study was to clarify the role of eNOS-derived NO onExpand
  • 2
Expression of NADH/NADPH Oxidase p22phox in Human Coronary Arteries
Background—NADH/NADPH oxidase is an important source of superoxide in the vasculature. Recently, we found that polymorphism of the gene p22phox, a critical component of this oxidase, is associatedExpand
Expression of Glutaredoxin in Human Coronary Arteries
Oxidative stress is considered an important factor in atherogenesis. Mammalian cells have a complex network of antioxidants such as catalase, superoxide dismutase, and glutathione peroxidase.Expand
  • 1