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  • Haruna Ui, Tsugunobu Andoh, Jung-Bum Lee, Hiroshi Nojima, Yasushi Kuraishi
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2006
  • The pruritogenic potency of tryptase and its involvement in anti-pruritic effect of intravenous nafamostat mesilate (NFM) were studied in mice. An intradermal injection of tryptase (0.05-1 ng/site)Expand
  • Takashi Sasamura, Shigenobu Nakamura, +5 authors Yasushi Kuraishi
  • Medicine
  • European journal of pharmacology
  • 2002 (First Publication: 1 April 2002)
  • The present study was conducted to clarify whether relief from cancer pain by morphine would suppress tumor growth and metastasis. When given orthotopic inoculation of B16-BL6 melanoma cells into theExpand
  • Tsugunobu Andoh, Yumi Nishikawa, Tomomi Yamaguchi-Miyamoto, Hiroshi Nojima, Shu Narumiya, Yasushi Kuraishi
  • Biology, Medicine
  • The Journal of investigative dermatology
  • 2007 (First Publication: 1 August 2007)
  • Thromboxane A2 (TXA2), a metabolite of arachidonic acid produced by cyclooxygenase and thromboxane synthase, is thought to participate in chronic dermatitis. This study investigated the involvementExpand
  • Tatsuya Maekawa, Hiroshi Nojima, Yasushi Kuraishi, Kazuo Aisaka
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2006 (First Publication: 1 August 2006)
  • JTE-907, N-(benzo[1,3]dioxol-5-ylmethyl)-7-methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3-carboxamide, is a selective cannabinoid CB2 receptor antagonist/inverse agonist. The anti-pruritic activityExpand
  • Hiroshi Nojima, Earl E. Carstens
  • Medicine, Chemistry
  • Journal of Pharmacology and Experimental…
  • 2003 (First Publication: 1 July 2003)
  • We investigated the role of serotonin (5-hydroxytryptamine; 5-HT)2 and 5-HT3 receptor subtypes in acute itch-associated scratching behavior as well as in an allergic pruritus model in rats.Expand