Hiroshi Mitsushio

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This report describes the effect of chronic dietary treatment with antidepressants or antimanic drugs on brain Met-enkephalin-like immunoreactivity in the rat. The chronic treatment was administered through food containing 250–1000 mg desipramine, imipramine or clomipramine, 200–800 mg amoxapine or mianserin, 750–1500 mg lithium chloride, or 50 mg(More)
Twenty-seven patients who suffered from alcohol dependence syndrome and who were admitted to the Department of Psychiatry at NCNP were investigated for impaired sleep. The incidence of "insomnia night", when a patient has trouble getting sufficient sleep even after taking additional drugs for insomnia, was used as the index for impaired sleep. "Insomnia(More)
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