Hiroshi Ikeoka

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Our previous investigation using normal guinea pigs disclosed that, like respiratory mucosa, the middle ear lining has ciliary activity, and that this ciliary activity becomes more active as the location becomes more distal to the eustachian tube. In this experimental study, the effects of Staphylococcus aureus on the middle ear lining was examined from(More)
Since the middle ear lining is an extension and a modification of the respiratory mucosa, it is conceivable that it has a mucociliary system and it plays an important role in clearance of the tympanic cavity. It was already noted in morphological studies that the middle ear lining had ciliated cells. To our knowledge, however, ciliary activity has never(More)
The ciliary activity in some pathological middle ear lining was discussed with special reference to the morphology of the epithelial cells in this paper. The changes in ciliary activity due to in vitro Staphylococcus aureus injection did not practically show any differences between the sites. On the other hand, the time-course changes in ciliary activity(More)
Ten guinea pigs were irradiated with 30 Gy of x-radiation. Five were killed on the eighth day after irradiation, and the remainder were killed at the sixteenth day after irradiation. At the time of death, examination was made of the ciliary activity and the fine structure of the middle ear mucosa. Serous effusion was found in each tympanic cavity of all(More)
Guinea pigs were exposed to 400 ppm or 5500 ppm of isopropyl alcohol (IPA) for 24 successive hours, and then middle ear mucosal samples in both proximal and distal sites to the eustachian tube were obtained for functional and morphological examinations. The ciliary activity was examined according to the photoelectric method of Ohashi and Nakai. The(More)
Single field, fixed irradiation of bilateral tympanic cavities using 200-kV x-rays was administered to five guinea pigs. The irradiation dose was 30 Gy. They were killed immediately after irradiation, and bilateral middle ear mucosa was examined for ciliary activity and epithelial structure. Significant deterioration of the ciliary activity in the middle(More)
We have studied the ciliary activity of the pharyngeal epithelium on adenoids obtained from patients with recurrent otitis media with effusion to assess indirectly the ciliary activity in the Eustachian tube. In conclusion, the following has been speculated from the present study: (1) middle ear effusions depress the ciliary activity; and (2) recovery of(More)