Hiroshi Deguchi

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In many patients with deep vein thrombosis and pulmonary embolism (venous thromboembolism, VTE), biomarkers or genetic risk factors have not been identified. To discover novel plasma metabolites associated with VTE risk, we employed liquid chromatography-mass spectrometry-based untargeted metabolomics, which do not target any specific metabolites. Using the(More)
Replication is essential in science and agent-based computational social science is no exception. We present results from a replication of the Sugarscape model (Eptstein and Axtell, 1996) as initially presented in Growing Artificial Societies (GAS). Sugarscape is a classic agent-based model and contemporary simulation toolkits usually only have a partial(More)
Blood coagulation reactions are strongly influenced by phospholipids, but little is known about the influence of sphingolipids on coagulation mechanisms. Lysosulfatide (lyso-SF) (sulfogalactosyl sphingosine) prolonged factor Xa (fXa) 1-stage plasma clotting assays, showing it had robust anticoagulant activity. In studies using purified clotting factors,(More)