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Two Cases of Renal Cell Carcinoma Harboring a Novel STRN-ALK Fusion Gene
Anaplastic lymphoma kinase (ALK) translocation renal cell carcinomas (RCCs) have been reported by several independent groups in recent times. The clinical behavior and histopathologic characteristicsExpand
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Clinicopathological features of neoplasms with neuroendocrine differentiation occurring in the liver
Background/aims We investigated the clinicopathological features of hepatic neuroendocrine tumours (NET) and neuroendocrine carcinoma (NEC), which remain largely unknown. Material and methods WeExpand
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Insulinoma-associated protein 1 (INSM1) is a useful marker for pancreatic neuroendocrine tumor
Insulinoma-associated protein 1 (INSM1) is an important biomarker of Achaete-scute homolog-like 1-driven pathways. For diagnosis of pancreatic neuroendocrine tumors (PanNET), chromogranin A (CGA),Expand
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Markers for microvascular invasion in hepatocellular carcinoma: Where do we stand?
Annette S. H. Gouw, Charles Balabaud, Hironori Kusano, Satoru Todo, Takafumi Ichida, and Masamichi Kojiro Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen,Expand
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Pegylated Interferon-α2a Inhibits Proliferation of Human Liver Cancer Cells In Vitro and In Vivo
Purpose We investigated the effects of pegylated interferon-α2a (PEG-IFN-α2a) on the growth of human liver cancer cells. Methods The effect of PEG-IFN-α2a on the proliferation of 13 liver cancer cellExpand
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  • Open Access
Clinical, Pathologic, and Genetic Features of Neonatal Dubin‐Johnson Syndrome: A Multicenter Study in Japan
Objective To clarify the clinical, pathologic, and genetic features of neonatal Dubin‐Johnson syndrome. Study design Ten patients with neonatal Dubin‐Johnson syndrome were recruited from 6 pediatricExpand
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Intraductal neoplasm of the intrahepatic bile duct: clinicopathological study of 24 cases.
AIM To investigate the clinicopathological features of intraductal neoplasm of the intrahepatic bile duct (INihB). METHODS Clinicopathological features of 24 cases of INihB, which were previouslyExpand
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Pathomorphologic study of undifferentiated carcinoma in seven cases: relationship between tumor and pancreatic duct epithelium.
BACKGROUND/PURPOSE By the time undifferentiated carcinoma is detected, it has formed a large mass, and it is reportedly difficult to pathologically observe its relationship with the pancreatic duct.Expand
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Growth inhibitory effect of an injectable hyaluronic acid-tyramine hydrogels incorporating human natural interferon-α and sorafenib on renal cell carcinoma cells.
UNLABELLED Immunotherapy including interferon-alpha (IFN-α) is one of the treatment options for metastatic renal cell carcinoma (mRCC) patients. Despite clinical benefits for the selected patients,Expand
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Antiproliferative effects of sorafenib and pegylated IFN-α2b on human liver cancer cells in vitro and in vivo
Novel therapeutic strategies are needed to treat patients with advanced hepatocellular carcinoma (HCC). Combination therapy of sorafenib and type I interferon (IFN) has substantial activity inExpand
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  • Open Access