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The purpose of this study was to determine whether arterial spin labelling (ASL) at 3-T MR imaging can be used to discriminate individuals with Alzheimer's disease (AD) from cognitively normal subjects. Twenty AD patients and 23 cognitively normal control subjects were studied using ASL on a 3-T MR imager. Absolute regional cerebral blood flow (rCBF) maps(More)
Our purpose was to reveal potential regional variations in water molecular diffusivity within each cerebral hemisphere and across the right and left hemispheres. Diffusion-weighted images of 44 healthy right-handed adult male subjects were obtained using a diffusion tensor imaging sequence. Mean diffusivity (MD) values in subcortical white matter (WM)(More)
PURPOSE the purpose of this study was to examine interhemispheric asymmetry in volume of the caudate nucleus and its age dependency. METHODS high-resolution T1-weighted brain magnetic resonance (MR) images were obtained for each subject using a 3-dimensional fast field-echo pulse sequence. The volumes of the bilateral caudate nuclei on MR images were(More)
RATIONALE AND OBJECTIVES The relative roles of arterial spin-labeling (ASL) perfusion imaging and magnetic resonance morphological assessment in diagnosing Alzheimer's disease (AD) have not been established. Our purposes were to directly compare the diagnostic performance of ASL regional cerebral blood flow (rCBF) measurement and that of morphological(More)
PURPOSE The purpose of this study was to determine the optimal computational options in voxel-based morphometry (VBM) for discrimination between Alzheimer's disease (AD) patients and healthy control (HC) subjects. MATERIALS AND METHODS Structural magnetic resonance images of 24 AD patients and 26 HC subjects were analyzed using VBM to determine brain(More)
OBJECTIVE The aim of this study was to assess the feasibility of ultrashort echo time (UTE) imaging in the visualization of middle ear ossicles in normal subjects. METHODS 12 young adult volunteers (males/females = 6/6, age 25-44 years, mean 30.3 years) with normal hearing levels underwent MRI studies using a 3.0 T clinical unit with an eight-channel(More)
INTRODUCTION Shared rotating control acquisition can shorten the imaging time of territorial arterial spin labeling (tASL) by 33% compared with the normal control acquisition scheme but potentially results in an inaccurate estimate of vascular territories due to imperfect magnetization transfer compensation. Our purpose was to validate the accuracy of the(More)
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