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  • Hironao Tamai, Tetsuo Sudo, +5 authors Takehiko Sasazuki
  • Medicine
  • Annals of Internal Medicine
  • 1996 (First Publication: 1 March 1996)
  • Objective: To determine the association between HLA class II genes and methimazole-induced agranulocytosis in patients with Graves disease. Design: Case-control study. Setting: Kuma Hospital, whichExpand
  • Hironao Tamai, Susumu Kato, Y Horie, Eiji Ohki, Hirokazu Yokoyama, Hiromasa Ishii
  • Psychology, Medicine
  • Alcoholism, clinical and experimental research
  • 2000 (First Publication: 1 March 2000)
  • BACKGROUND Endotoxin has been implicated in the pathogenesis and progression of alcoholic liver disease. Not only inactivation of reticuloendothelial function, which reduces clearance of endotoxin,Expand
  • Hironao Tamai, Kanji Kasagi, +7 authors Shigenobu Nagataki
  • Medicine
  • The Journal of clinical endocrinology and…
  • 1989 (First Publication: 1 July 1989)
  • Graves' disease may result eventually in hypothyroidism in approximately 5-20% of patients. In a few such patients hypothyroidism was associated with TSH-blocking antibodies, but whether theExpand