Learn More
The effect of variation in urinary flow rate (ml urine min-1, UF) on adjusted and non-adjusted urinary excretion of metals and organic substances was examined in ten 'healthy' men. The effect of UF was found to be eliminated when urinary concentrations of lead (Pb), hippuric acid (HA), delta-aminolevulinic acid (ALA) and coproporphyrin (CP) were adjusted to(More)
To evaluate the reversibility of the effect of lead on psychological performance, five performance scale subtests of the Wechsler Adult Intelligence Scale were conducted twice at two-yr intervals on 17 gun-metal foundry workers who had initial blood lead (BPb) concentrations of 30-64 (median 40) micrograms/dl. The results indicated that psychological(More)
The effects of urinary volume on adjusted and nonadjusted urinary excretion of 11 heavy metals and organic substances were examined in relation to plasma and erythrocyte concentrations in 19 metal workers under conditions of water restriction and loading. Blood lead concentrations in these workers ranged from 25 to 59 micrograms/dl. The results indicated(More)
The effects of urinary volume on daily urinary excretion of seven heavy metals and four organic substances were examined in relation to the changes in their plasma and erythrocyte concentrations and urinary creatinine excretion in 19 metal workers. The examination was conducted under the conditions of water restriction and loading for six days. The major(More)
To estimate "filterable" plasma concentration (FPx), glomerular filtration, tubular balance, and renal clearance of heavy metals and organic substances, the authors examined the regressions of the 24-hr urinary excretion on glomerular filtration rate [GFR, 24-hr endogenous creatinine (Cn) clearance] in 19 gun-metal foundry workers with blood lead (Pb)(More)
To elucidate circadian rhythms (variation within a day) of 7 toxic or essential metals in plasma and erythrocytes in relation to the rhythms in urine in men, 19 male metal foundry workers were examined; they were exposed to lead (Pb), zinc (Zn) and copper (Cu) occupationally but separated from the exposure during the study. Circadian rhythms were found for(More)
Subclinical central and peripheral nervous system dysfunction among lead-exposed workers was studied by measuring short-latency somatosensory evoked potentials (SSEP) and maximal motor and sensory nerve conduction velocities (MCV and SCV) following stimulation of the median nerve at the wrist. The examinations were conducted in 20 gun-metal foundry workers(More)
To evaluate the interactive effects of lead, zinc, and copper on the peripheral nervous system in man, we measured maximal motor and sensory conduction velocities (MCV and SCV) in the distal radial and median nerves in 19 gun metal foundry workers with asymptomatic increased absorption of these metals twice at a 12-month interval. The workers' initial blood(More)
BACKGROUND Although vital statistics have indicated large Japanese-American differences in mortality rates for coronary heart disease (CHD), the magnitude of difference has not been documented well using comparable validation of cause of death. METHODS Population-based fatal CHD data were compared between the Oita Cardiac Death Survey, Japan and the(More)
Previous studies have shown that serum concentrations of lipoprotein(a) [Lp(a)] are markedly different among different ethnic groups. We examined the serum levels of total cholesterol, high density lipoprotein (HDL) cholesterol and Lp(a) in apparently healthy subjects aged 20-69 years in Japan (n = 865) and the Dominican Republic (n = 1,893). Dominicans had(More)