Hiroko Nakamura

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Repolarization of cardiac action potentials is regulated by several types of K(+) currents. The present study examined the presence and functional significance of rapid delayed rectifier (I(Kr)) in left and right atrial myocytes of mouse heart, using whole-cell patch-clamp method. The functional role of ultrarapid delayed rectifier (I(Kur)) in the(More)
Treatment of patients with multiple myeloma (MM) has drastically changed with the introduction of novel agents such as thalidomide, lenalidomide, and bortezomib, but treatment outcome of elderly patients has remained dismal mainly due to toxicities. We report an 82-year-old MM patient attaining stringent complete response (sCR) at 12 months with a daily(More)
Defective route finding is a symptom in which an indivisual demonstrates inhibility to find the way in the familiar places. This symptom arises from lesions at the right parieto-occipital region and the right posterior part of the splenium of the corpus callosum. We present a case of defective route finding resulting from the right anterior thalamic(More)
Background: Primary malignant melanoma of the vagina is an aggressive and very rare malignancy. This tumor constitutes less than 3% of vaginal cancers and only 0.3-0.8% of all melanomas in women. The overall prognosis for patients with vaginal melanoma is poor. Furthermore, once a recurrence is noted, survival is extremely poor, with a mean survival time of(More)
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