Hiroko Nakamoto

Learn More
Small heat shock proteins are ubiquitous proteins found throughout all kingdoms. One of the most notable features is their large oligomeric structures with conserved structural organization. It is well documented that small heat shock proteins can capture unfolding proteins to form stable complexes and prevent their irreversible aggregation. In addition,(More)
The psaI gene encoding the 4 kDa polypeptide subunit (PsaI) of the photosystem I was cloned from the Synechocystis sp. PCC 6803, a readily transformable cyanobacterium. The gene is located immediately downstream of the psaL gene in this cyanobacterial genome and encodes a polypeptide of 40 amino acid residues with a deduced molecular mass of 4,413 Da. The(More)
Mutant strains of the unicellular cyanobacterium Synechocystis sp. PCC 6803, in which the psaK gene was insertionally inactivated by targeted mutagenesis, were constructed. The gene is one of the two potential PsaK-coding genes which have been found as a result of the genome project with this cyanobacterium. One of the mutants was characterized in detail. A(More)
Many tumor-suppressor genes are involved in the development and progression of cellular malignancy. To understand the functional role of tumor-suppressor genes in melanoma and to identify the human chromosome that carries these genes, we transferred individually each normal human chromosome, except for the Y chromosome, into the mouse melanoma cell line(More)
  • 1